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Fig. 2 | BMC Medicine

Fig. 2

From: A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP)

Fig. 2

Power curves for excluding a proportion of unfavourable outcomes under different assumptions of the true proportion, assuming (a) 60, (b) 80, and (c) 100 patients per arm for a STEP trial. Numbers on graphs show the proportion of unfavourable outcomes that could be excluded at the upper bound of the 90 % two-sided confidence interval (95 % one-sided confidence interval, CI) with 80 % and 90 % power

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