Skip to main content
Fig. 6 | BMC Medicine

Fig. 6

From: A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP)

Fig. 6

Results of a simulation study using RIFAQUIN data with a flat prior. Charts show the distribution of the predictive probability of the unfavourable proportion in the phase III trial being lower than the threshold p1 from 10,000 random draws from the RIFAQUIN trial data for various sizes of STEP trials (60, 80, 100 per arm) and thresholds p1 = 5 % (a), 8 % (b), and 10 % (c)

Back to article page