Table 2 Characteristics of studies evaluating OncotypeDX®
From: Incorporation of tissue-based genomic biomarkers into localized prostate cancer clinics
First author and year | Number of cases | Study population | End point | Main results |
|---|---|---|---|---|
Klein et al. [30] 2014 | 608 patients | Radical prostatectomy and Prostate biopsies | Metastases after radical prostatectomy and adverse pathology in radical prostatectomy specimen | Prediction of adverse pathology at radical prostatectomy using prostate biopsies tissue. |
Cullen et al. [31] 2015 | 431 patients | Prostate biopsies in very low, low and intermediate Prostate cancer patients | Adverse radical prostatectomy pathology and biochemical recurrence | Increased BCR risk at univariable analyses and after adjusting for risk groups at multivariable using prostate biopsy tissue |