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Fig. 3 | BMC Medicine

Fig. 3

From: Enhanced antibiotic distribution strategies and the potential impact of facial cleanliness and environmental improvements for the sustained control of trachoma: a modelling study

Fig. 3

Prevalence of infection and active disease in 0–9-year olds when comparing single-dose annual MDA to double-dose annual MDA (conducted 2 weeks apart) within a mesoendemic community for 3 years. We assumed 80 % coverage, and 65 % and 85 % efficacy of the antibiotic for high and low bacterial loaders, respectively. Scenario 1: a prevalence of infection and b active disease with single-dose annual MDA, with a 0 % decline in β. Scenario 2: c prevalence of infection and d active disease with double-dose annual MDA applied 2 weeks apart, with a 0 % decline in β. Scenario 3: e prevalence of infection and f active disease with single-dose annual MDA. Scenario 4: g prevalence of infection and h active disease with double-dose annual MDA applied 2 weeks apart. While also modelling an instantaneous drop in β, we present a range of reductions in β. Different coloured lines represent different percentage declines in the value of β, ranging from 0–50 %. Grey dashed line indicates 5 % prevalence, where < 5 % prevalence of active disease is the GET 2020 target level

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