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Table 1 Demographic and baseline characteristics

From: Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data

  Africa Asia South America
  n evaluated n (%) or median (Range) n evaluated n (%) or median (Range) n evaluated n (%) or median (Range)
Age       
  < 1 year 34361 2502 (7) 13545 60 (0) 915 0 (0)
 1–4 years 34361 20473 (60) 13545 1377 (10) 915 0 (0)
 5–11 years 34361 6775 (20) 13545 3601 (27) 915 111 (12)
  ≥ 12 years 34361 4611 (13) 13545 8507 (63) 915 804 (88)
Age (years) 34361 3.3 (0–86.7) 13545 15.0 (0–88.0) 915 23.0 (5.0 – 65.0)
Haemoglobin (g/dL) 24771 9.9 (5.0–19.7) 3139 11.1 (5.0–20) 603 12.2 (7.0–17.3)
Haematocrit (%) 5938 32.8 (15.0–49.8) 8076 36.0 (15.0–50.0) 604 37.0 (18.0 – 50.0)
Derived haemoglobin (g/dL) 26806 9.9 (3.6–19.7) 10937 11.6 (3.6–20) 606 12.2 (7.0–17.3)
Anaemia 26806 13313 (50) 10937 3882 (26) 606 48 (8)
Temperature (°C) 33776 37.9 (34.0–41.5) 10828 37.7 (34.0–42.0) 914 37.5 (35.1 – 42.0)
Fever 34199 21213 (62) 10981 6862 (53) 914 438 (48)
History of fever 7244 6826 (94) 2515 2291 (91) 0 . (.)
Parasitaemia (/μL) 34376 20560 (2–250000) 13546 9720 (0–249818) 915 4514 (0–149925)
Hyperparasitaemia 34376 3223 (9) 13546 1908 (14) 915 3 (0)
Mixed infection 34377 0 (0) 13546 903 (7) 917 0 (0)
Sex (male) 33411 17223 (52) 13243 8015 (61) 917 566 (62)
Weight-for-age z-score       
  < 5 years 21765 –0.89 (–5.93 to 4.69) 1403 –1.58 (–5.88 to 4.71) 0
  < 1 year 2323 –0.68 (–5.93 to 4.69) 56 –0.67 (–4.45 to 4.71) 0
 1–2 years 9708 –0.96 (–5.91 to 4.54) 414 –1.61 (–5.53 to 4.37) 0
 3–4 years 8305 –0.99 (–5.3 to 4.38) 869 –1.69 (–5.88 to 2.62) 0
Underweight       
  < 5 years 21765 3918 (18) 1403 517 (37) 0
  < 1 year 2323 373 (16) 56 8 (14) 0
 1–2 years 9708 1846 (19) 414 150 (36) 0
 3–4 years 8305 1503 (18) 869 338 (39) 0
Transmission intensity       
 Low 34105 10063 (30) 13246 11884 (90) 917 917 (100)
 Moderate 34105 10659 (31) 13246 1362 (10) 917 0 (0)
 High 34105 13383 (39) 13246 0 (0) 917 0 (0)
  1. Derived haemoglobin, conversion from haematocrit: haemoglobin = (haematocrit–5.62)/2.60 [40]; Anaemia, haemoglobin < 10 g/dL; Fever, temperature > 37.5 °C; Hyperparasitaemia, parasitaemia > 100,000 parasites per μL; Weight-for-age z-score, calculated using “igrowup” package developed by WHO [41] in children < 5 years of age; Underweight, weight-for-age z-scores < –2