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Table 1 Demographic and baseline characteristics

From: Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data

 

Africa

Asia

South America

 

n evaluated

n (%) or median (Range)

n evaluated

n (%) or median (Range)

n evaluated

n (%) or median (Range)

Age

      

  < 1 year

34361

2502 (7)

13545

60 (0)

915

0 (0)

 1–4 years

34361

20473 (60)

13545

1377 (10)

915

0 (0)

 5–11 years

34361

6775 (20)

13545

3601 (27)

915

111 (12)

  ≥ 12 years

34361

4611 (13)

13545

8507 (63)

915

804 (88)

Age (years)

34361

3.3 (0–86.7)

13545

15.0 (0–88.0)

915

23.0 (5.0 – 65.0)

Haemoglobin (g/dL)

24771

9.9 (5.0–19.7)

3139

11.1 (5.0–20)

603

12.2 (7.0–17.3)

Haematocrit (%)

5938

32.8 (15.0–49.8)

8076

36.0 (15.0–50.0)

604

37.0 (18.0 – 50.0)

Derived haemoglobin (g/dL)

26806

9.9 (3.6–19.7)

10937

11.6 (3.6–20)

606

12.2 (7.0–17.3)

Anaemia

26806

13313 (50)

10937

3882 (26)

606

48 (8)

Temperature (°C)

33776

37.9 (34.0–41.5)

10828

37.7 (34.0–42.0)

914

37.5 (35.1 – 42.0)

Fever

34199

21213 (62)

10981

6862 (53)

914

438 (48)

History of fever

7244

6826 (94)

2515

2291 (91)

0

. (.)

Parasitaemia (/μL)

34376

20560 (2–250000)

13546

9720 (0–249818)

915

4514 (0–149925)

Hyperparasitaemia

34376

3223 (9)

13546

1908 (14)

915

3 (0)

Mixed infection

34377

0 (0)

13546

903 (7)

917

0 (0)

Sex (male)

33411

17223 (52)

13243

8015 (61)

917

566 (62)

Weight-for-age z-score

      

  < 5 years

21765

–0.89 (–5.93 to 4.69)

1403

–1.58 (–5.88 to 4.71)

0

  < 1 year

2323

–0.68 (–5.93 to 4.69)

56

–0.67 (–4.45 to 4.71)

0

 1–2 years

9708

–0.96 (–5.91 to 4.54)

414

–1.61 (–5.53 to 4.37)

0

 3–4 years

8305

–0.99 (–5.3 to 4.38)

869

–1.69 (–5.88 to 2.62)

0

Underweight

      

  < 5 years

21765

3918 (18)

1403

517 (37)

0

  < 1 year

2323

373 (16)

56

8 (14)

0

 1–2 years

9708

1846 (19)

414

150 (36)

0

 3–4 years

8305

1503 (18)

869

338 (39)

0

Transmission intensity

      

 Low

34105

10063 (30)

13246

11884 (90)

917

917 (100)

 Moderate

34105

10659 (31)

13246

1362 (10)

917

0 (0)

 High

34105

13383 (39)

13246

0 (0)

917

0 (0)

  1. Derived haemoglobin, conversion from haematocrit: haemoglobin = (haematocrit–5.62)/2.60 [40]; Anaemia, haemoglobin < 10 g/dL; Fever, temperature > 37.5 °C; Hyperparasitaemia, parasitaemia > 100,000 parasites per μL; Weight-for-age z-score, calculated using “igrowup” package developed by WHO [41] in children < 5 years of age; Underweight, weight-for-age z-scores < –2