Fig. 1
From: How important is gametocyte clearance after malaria therapy?
The life cycle of Plasmodium falciparum, demonstrating how onward transmission occurs from one human host to the next. Drugs with “transmission-blocking” properties can act on any of the sexual stages of the parasite (gametocytes from stage I to V) occurring within the human host (pink-shaded area). However, because a mosquito’s blood meal will contain concentrations of any drug present at the time of biting, drugs administered to humans can also have transmission-blocking potential through their activity on stages present in the mosquito mid-gut (yellow-shaded area)