Table 1 Parameter values of the dynamic model
From: Fast and accurate dynamic estimation of field effectiveness of meningococcal vaccines
Description | Value | Source | |
|---|---|---|---|
α | Yearly crude birthrates | Between 11.3 and 13.0 per 1000 population, variable by year | [47] |
μ a | Yearly mortality rates | Variable by age (Additional file 1: Figure S2) | [47] |
τ car | Duration of carriage (1/ρ) | 6 [3–9] months | |
β a | Quarterly rates of infection given contacts with carriers | Variable by age (Additional file 1: Figure S4) | Fitted |
\(m_{aa'}\phantom {\dot {i}\!}\) | Daily contact rates matrix | Variable by age of subject and contact (Additional file 1: Figure S3) | [48] |
θ a | Quarterly risks of disease given infection | Variable by age (Additional file 1: Figure S5) | Fitted |
γ a | Quarterly fraction of population vaccinated | MenB: 95 % of 1 year olds MenC: variable by age and schedule | MenB: assumed MenC: [52] |
τ imm,a | Duration of immunity to disease | MenB: 18 months MenC: variable by age (15 [9–24] mths, 5 years, 10 years) | |
ω a | Waning of immunity fraction | MenB: 100 % MenC: 58.4 % | MenB: assumed MenC: [26] |