Table 1 Model parameters varied in the fitting and simulation procedures to cover their uncertainty and the values varied for each parameter
From: Investigating the pertussis resurgence in England and Wales, and options for future control
Parameter | Values varied |
|---|---|
Average duration of natural immunity (ω) | 10, 15, 20, 25, 30, 35, 40, 45 and 50 years |
Scale parameter for the proportion of second + infections that are notified compared to proportion of first infections in unvaccinated individuals (α2/α1) | 10 % (1/10), 5 % (1/20), 3.3 % (1/30), 2.5 % (1/40) and 2 % (1/50) |
Degree of wP and aP vaccine protection against infection (πwp and πap) | 10, 20, 30, 40, 50, 60, 70, 80 and 90 % |
Average duration of wP and aP vaccine protection against infection and disease (wPω and aPω) | 5, 7.5, 10, 12.5, 15, 17.5, 20, 22.5, 25, 27.5 and 30 years |