Fig. 1
From: Urine metabolome profiling of immune-mediated inflammatory diseases
Metabolic reaction network illustrating metabolic signatures associated to IMIDs. Red-shaded metabolites have been associated to IMIDs in the current study. The associated IMIDs are displayed in a text box next to the corresponding metabolite. Disease associations meeting multiple test correction (FDR < 0.05) at the discovery and validation stages are displayed in green letters. Nominal disease associations (P < 0.05) at the discovery and validation stages are displayed in red letters. The metabolite reaction linking hippurate and glycine is only conducted through the activity of the gut microbiota