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Table 3 Pre-pregnancy maternal BMI and newborn telomere length

From: Maternal pre-pregnancy body mass index and newborn telomere length

 

Cord blood telomere length (n = 743)

Placental telomere length (n = 702)

Percentage change (95 % CI)

P value

Percentage change (95 % CI)

P value

Unadjusted model

−0.52 (−0.85 to −0.20)

0.002

−0.60 (−0.99 to −0.20)

0.003

Model A

−0.48 (−0.80 to −0.15)

0.004

−0.60 (−1.00 to −0.20)

0.003

Model B

−0.50 (−0.83 to −0.17)

0.003

−0.66 (−1.06 to −0.25)

0.002

  1. Estimates are presented as a percentage change in average relative telomere length for each kg/m2 BMI increase
  2. Model A, adjustment for paternal and maternal age at birth, maternal education, newborn gender, gestational age, and birth weight
  3. Model B, additionally adjusted for maternal smoking status, parity, newborn ethnicity, pregnancy complications, and cesarean section