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Fig. 5 | BMC Medicine

Fig. 5

From: A novel approach to identifying patterns of human invasion-inhibitory antibodies guides the design of malaria vaccines incorporating polymorphic antigens

Fig. 5

Overlap and allele specificity of AMA1-specific invasion-inhibitory antibodies. a Overlap in AMA1-specific invasion-inhibitory activity for the three AMA1 alleles with the highest prevalence of inhibitory antibodies. Numbers of PNG individuals whose serum showed specific inhibition of each line are shown. b Proportion of PNG samples (n = 98 or 99) showing specific inhibition of genetically engineered P. falciparum expressing one allele of AMA1 that also inhibited growth of lines expressing other AMA1 alleles. Error bars indicate + SEM

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