Table 3 Other outcomes, change in outcome at study end from baseline

BMI, kg/m²

–3.7^* (–4.7 to –2.7)

–3.6^* (–4.8 to –2.3)

–0.1 (–1.7 to 1.4)

0.85

Waist circumference, cm

–11^* (–14 to –8)

–8^* (–12 to –5)

–3 (–7 to 2)

0.21

SBP, mmHg

–1 (–6 to 3)

–1 (–6 to 3)

0 (–6 to 6)

0.94

DBP, mmHg

0 (–3 to 3)

–1 (–4 to 2)

1 (–3 to 5)

0.62

Handgrip, kg

1.7 (–0.5 to 3.8)

–1.9 (–4.3 to 0.5)

3.6 (0.4 to 6.7)

0.03

ALM/height², kg/m²

0.12 (–0.02 to 0.26)

–0.33^* (–0.50 to –0.15)

0.45 (0.22 to 0.67)

<0.001

Step count per day

931^* (116 to 1746)

606 (–186 to 1399)

325 (–794 to 1443)

0.56

Activity, %/day

1.5^* (0.1 to 2.9)

0.7 (–0.6 to 2.1)

0.76 (–1.2 to 2.7)

0.43

Physical function test, sec

–3.1^* (–4.8 to –1.5)

–2.7^* (–4.1 to –1.3)

–0.4 (–2.6 to 1.7)

0.67

TT, nmol/L, ECLIA

7.4^* (5.7 to 9.1)

1.8^* (0.4 to 3.1)

5.5 (3.4 to 7.7)

<0.001

cFT, pmol/L, ECLIA

49^* (37 to 60)

4 (–3 to 10)

46 (32 to 59)

<0.001

SHBG, nmol/L

4^* (2 to 6)

7^* (3 to 10)

–3 (–6.4 to 1.1)

0.16

LH, IU/L

–4.0^* (–4.7 to –3.4)

0.2 (–0.5 to 1.0)

–4.3 (–5.2 to –3.3)

<0.001

Fasting glucose, mmol/L

–0.5^* (–0.8 to –0.25)

–0.3^* (–0.5 to 0.0)

–0.3 (–0.6 to 0.1)

0.19

HOMA-IR

–0.8^* (–1.1 to –0.5)

–0.6^* (–0.9 to –0.2)

–0.2 (–0.7 to 0.3)

0.38

HbA1c, %

–0.5^* (–0.6 to –0.3)

–0.3^* (–0.5 to –0.2)

–0.1 (–0.3 to 0.1)

0.19

Cholesterol, mmol/L

–0.18 (–0.4 to 0.0)

0.0 (–0.2 to 0.2)

–0.19 (–0.5 to 0.1)

0.23

LDL-C, mmol/L

–0.1 (–0.3 to 0.1)

–0.1 (–0.3 to 0.2)

0.0 (–0.3 to 0.3)

0.88

HDL-C, mmol/L

0.1^* (0.1 to 0.2)

0.1^* (0.0 to 0.2)

0.0 (–0.1 to 0.1)

0.66

Triglycerides, mmol/L

–0.6^* (–0.9 to –0.4)

–0.4^* (–0.6 to –0.1)

–0.3 (–0.6 to 0.1)

0.17

Haematocrit

0.04^* (0.03 to 0.05)

–0.005^* (–0.009 to –0.001)

0.04 (0.03 to 0.05)

<0.001

Haemoglobin, g/L

14^* (11 to 17)

–2^* (–3 to 0)

15 (12 to 19)

<0.001

PSA, μg/L

0.3^* (0.2 to 0.5)

0.1^* (0.0 to 0.3)

0.2 (0.0 to 0.4)

0.10