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Table 1 Baseline characteristics of the different cohorts

From: Renal function estimation and Cockcroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: The Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives

Variables Population-based Cardiovascular risk Heart failure Post-myocardial infarction P value
Number of patients 2644 20,895 1801 28,771 <0.001
 Demographic
  Age, years 66.4 ± 14.1 66.7 ± 9.4 73.7 ± 10.4 65 ± 11.5 <0.001
  Male sex, n (%) 1359 (51.4) 14,083 (67.4) 1093 (60.7) 20,189 (70.2) <0.001
  Smokers, n (%) 400 (15.1) 5994 (28.8) 185 (10.7) 18,235 (63.4) <0.001
 Clinical and echocardiographic
  Hypertension, n (%) 1397 (53.1) 17,892 (85.6) 861 (47.8) 15,570 (54.1) <0.001
  Diabetes, n (%) 334 (12.7) 5164 (24.7) 541 (30.1) 7386 (25.7) <0.001
  SBP, mmHg 136 ± 18 159 ± 21 133 ± 24 122 ± 17 <0.001
  Heart rate, bpm 67 ± 12 71 ± 13 75 ± 15 76 ± 13 <0.001
  LVEF, %a 67 ± 8 56 ± 13 41 ± 15 34 ± 9 <0.001
  Height, m 1.67 ± 8.9 1.69 ± 9.5 1.66 ± 9.7 1.69 ± 9.4 <0.001
  Weight, kg 73.8 ± 13.9 80.7 ± 15.8 76.4 ± 18.2 79.1 ± 15.5 <0.001
 Laboratory
  Hemoglobin, g/dLa 13.9 ± 1.3 13.4 ± 1.9 13.2 ± 1.8 13.3 ± 1.7 <0.001
  Creatinine, mg/dL 0.96 ± 0.24 1.12 ± 0.25 1.24 ± 0.53 1.12 ± 0.32 <0.001
  MDRD4, mL/min/1.73 m2 77.1 ± 18.2 66.8 ± 15.3 63.3 ± 24.4 71.05 ± 39.61 <0.001
  CKD-EPI, mL/min/1.73 m2 74.6 ± 17.0 65.2 ± 15.4 59.3 ± 21.9 67.93 ± 20.75 <0.001
  CG-BSA, mL/min/1.73 m2 71.1 ± 20.6 64.6 ± 17.8 57.2 ± 25.5 68.32 ± 32.89 <0.001
 Follow-up and events
  Follow-up, years 4.2 (3.6–4.9) 5.0 (3.3–5.9) 2.6 (1.2–3.5) 1.0 (0.2–1.9) <0.001
  CVM, n (%) 52 (2.0) 785 (3.8) 283 (15.7) 4400 (15.3) <0.001
  1. N number, MI myocardial infarction, MV missing values, SBP systolic blood pressure, LVEF left ventricular ejection fraction, CVM cardiovascular mortality, CG-BSA Cockcroft–Gault formula adjusted for body surface area, MDRD4 modification of diet in renal disease-4 formula, CKDEPI Chronic Kidney Disease Epidemiology Collaboration equation
  2. Normally distributed variables are presented as mean ± standard deviation; skewed variables are presented as median (percentile 25–75); proportions are presented as absolute numbers (n) and proportions (%). P values for “between group differences” were determined by one-way analysis of variance (ANOVA) tests
  3. aThese variables present > 75% missing values in all populations, therefore they are not included in the adjusted models