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Table 2 Subgroup analyses (per 100 mg/day increase)

From: Dietary magnesium intake and the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality: a dose–response meta-analysis of prospective cohort studies

  N RR (95% CI) I2 (%) P value
Total cardiovascular disease
 Sex
  Male 3 0.98 (0.89–1.08) 0.0 0.959
  Female 4 0.94 (0.73–1.13) 79.9
 Case
  Mortality 8 0.93 (0.82–1.05) 63.9 0.255
  Incidence 3 1.10 (0.82–1.48) 82.7
 Location
  United States 3 1.07 (0.78–1.48) 86.2 0.606
  Europe 2 0.93 (0.81–1.05) 0.0
  Asia 5 0.99 (0.83–1.17) 70.8
Coronary heart disease
 Sex
  Male 3 0.89 (0.81–0.99) 3.5 0.409
  Female 4 0.95 (0.83–1.09) 51.8
Case
  Mortality 5 0.81 (0.69–0.95) 36.3 0.105
  Incidence 3 0.97 (0.90–1.05) 12.7
 Location
  United States 3 0.95 (0.88–1.03) 27.6 0.439
  Asia 4 0.84 (0.68–1.03) 42
Stroke
 Subtype
  Ischemic 10 0.93 (0.88–0.98) 28.9 0.285
  Hemorrhagic 9 0.97 (0.88–1.07) 29.0
 Sex
  Male 8 0.93 (0.89–0.98) 0.9 0.884
  Female 7 0.94 (0.87–1.02) 37.2
 Case
  Mortality 4 1.07 (0.90–1.28) 45.0 0.028
  Incidence 13 0.92 (0.89–0.95) 0.0
 Location
  United states 6 0.91 (0.87–0.95) 0.0 0.140
  Europe 6 0.93 (0.89–0.98) 0.0
  Asia 5 1.00 (0.80–1.23) 63.5
Type 2 diabetes
 Sex
  Male 5 0.85 (0.79–0.93) 48.3 0.381
  Female 9 0.81 (0.75–0.87) 65.8
 Location
  United States 11 0.81 (0.77–0.86) 63.2 0.968
  Asia 9 0.79 (0.69–0.90) 62.4
All-cause mortality
 Sex
  Male 2 0.91 (0.84–0.98) 0.0 0.745
  Female 3 0.88 (0.68–1.14) 62.5
 Location
  United States 2 0.77 (0.58–1.04) 46.9 0.134
  Europe 2 0.83 (0.66–1.06) 72.6
  Asia 3 0.98 (0.87–1.11) 51.5
  1. RR relative risk, 95% CI 95 confidence interval (lower limit–upper limit)