Epidemiological | Number of PM cases per month | |||||||
---|---|---|---|---|---|---|---|---|
Period | PCV7 serotype | P valueb | Delta6 serotypec | P value | Non-vaccine serotype | P value | Total | P value |
Baselined | 3.7 | – | 1.3 | – | 2.0 | – | 6.7 | – |
2003–2004 | –0.03 (–0.50 to 0.44) | 0.89 | +0.3 (–0.51 to 1.19) | 0.43 | +1.2 (0.34 to 2.03) | 0.006 | –1.2 (–2.60 to 0.18) | 0.09 |
2004–2005 | –0.2 (–0.75 to 0.26) | 0.35 | +0.5 (–0.35 to 1.41) | 0.24 | +1.8 (0.94 to 2.62) | <0.001 | +0.6 (–0.82 to 2.00) | 0.41 |
2005–2006 | –0.6 (–1.18 to –0.10) | 0.021 | +0.5 (–0.30 to 1.40) | 0.20 | +1.6 (0.73 to 2.44) | <0.001 | –0.4 (–1.79 to 1.01) | 0.58 |
2006–2007 | –0.1 (–0.68 to 0.40) | 0.60 | +1.3 (0.49 to 2.19) | 0.002 | +2.1 (1.23 to 2.93) | <0.001 | +1.5 (0.16 to 2.95) | 0.03 |
2007–2008 | –0.9 (–1.47 to –0.39) | <0.001 | +1.1 (0.28 to 2.00) | 0.009 | +2.4 (1.50 to 3.23) | <0.001 | +0.3 (–1.11 to 1.69) | 0.68 |
2008–2009 | –1.5 (–2.06 to –0.93) | <0.001 | +3.7 (2.83 to 4.55) | <0.001 | +3.3 (2.41 to 4.18) | <0.001 | +1.3 (–0.07 to 2.77) | 0.06 |
2009–2010 | –2.8 (–3.39 to –2.28) | <0.001 | +2.7 (1.81 to 3.56) | <0.001 | +3.1 (2.23 to 4.02) | <0.001 | +0.3 (–1.14 to 1.71) | 0.69 |
2010–2011 | –3.1 (–3.59 to –2.52) | <0.001 | +0.7 (–0.18 to 1.54) | 0.12 | +3.6 (2.74 to 4.45) | <0.001 | +0.6 (–0.66 to 6.44) | 0.11 |
2011–2012 | –2.2 (–2.78 to –1.73) | <0.001 | –0.4 (–1.26 to 0.45) | 0.35 | +4.5 (3.64 to 5.36) | <0.001 | +0.5 (–0.84 to 1.93) | 0.43 |
2012–2013 | –2.7 (–3.28 to –2.15) | <0.001 | –1.2 (–2.03 to –0.29) | 0.009 | +3.3 (2.42 to 4.20) | <0.001 | +0.5 (–0.92 to 1.94) | 0.48 |
2013–2014 | –3.1 (–3.70 to –2.47) | <0.001 | –1.1 (–1.96 to –0.25) | 0.010 | +2.8 (1.98 to 3.73) | <0.001 | –2.0 (–3.36 to –0.57) | 0.006 |