Table 1 Baseline and case characteristics: EPIC cohort breast cancer nested case-control study
Cases | Controls | |
|---|---|---|
Full study population, n | 2008 | 2008 |
Baseline characteristics, median (10 th –90 th percentiles) or n (%) | ||
Age at blood collection, years | 57 (45-64) | 57 (45-64) |
Age at menarche, years | 13 (11-15) | 13 (11-15) |
Premenopausal | 462 (23%) | 462 (23%) |
Postmenopausal | 1546 (77%) | 1546 (77%) |
HT use at blood collectiona | 755 (49%) | 755 (49%) |
Age at menopause, yearsa | 50 (43-55) | 50 (43-55) |
Completed term pregnancy | 1695 (84%) | 1733 (86%) |
Age at first term pregnancy,b years | 25 (20-31) | 24 (20-30) |
BMI, kg/m2 | 24 (21-31) | 24 (20-30) |
Case characteristics | ||
ER+ | 1622 (81%) | |
ER– | 386 (19%) | |
ER+/PR + c | 929 (63%) | |
ER–/PR– | 258 (17%) | |
Age at diagnosis, years | 61 (50-70) | |
Time between blood donation and diagnosis, years | 4.7 (1.2-8.1) | |
Osteoprotegerin concentrations, ng/mL, median (10 th –90 th percentiles) | ||
0.196 (0.138-0.282) | 0.197 (0.141-0.289) | |