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Table 1 Anthropometric and metabolic variables pre-surgery and 6 months after biliopancreatic diversion (BPD), laparoscopic greater curvature plication (LGCP) and laparoscopic adjustable gastric banding (LAGB) bariatric procedures

From: Impact of gut hormone FGF-19 on type-2 diabetes and mitochondrial recovery in a prospective study of obese diabetic women undergoing bariatric surgery

 

BPD

LGCP

LAGB

Pre-surgery

Post-surgery

Change (%)

Pre-surgery

Post-surgery

Change (%)

Pre-surgery

Post-surgery

Change (%)

n

12

15

12

Age, years

50.57 ± 5.88

53.24 ± 7.48

53.57 ± 11.26

EWL, %

30.67 ± 8.42****

17.36 ± 6.32

20.17 ± 9.36

Body weight, kg

127.7 ± 22.6

106.9 ± 18.5**

83.8 ± 3.0***

109.2 ± 16.5

97.6 ± 14.1**

89.5 ± 3.2

119.6 ± 19.1

105.3 ± 18.3**

88.1 ± 5.7

BMI, kg/m2

46.45 ± 7.75

39.01 ± 6.37**

84.1 ± 3.5***

40.41 ± 5.54

36.05 ± 4.62**

89.3 ± 3.4

43.95 ± 6.60

38.31 ± 7.05**

88.90 ± 4.9

WHR, cm

0.93 ± 0.07

0.90 ± 0.07

97.7 ± 9.9

0.88 ± 0.10

0.87 ± 0.08

100.1 ± 11.1

0.90 ± 0.04

0.88 ± 0.04

98.5 ± 5.9

Body fat, %

49.59 ± 3.70

44.68 ± 4.62**

90.2 ± 6.6

48.49 ± 3.78

44.90 ± 3.71**

92.7 ± 4.6

49.54 ± 3.44

46.39 ± 4.45*

93.6 ± 5.6

Glucose, mmol/L

8.40 ± 2.57

7.01 ± 1.73

89.1 ± 30.1

8.93 ± 2.11

7.34 ± 1.64*

84.4 ± 16.9

9.30 ± 2.65

7.07 ± 1.56**

77.4 ± 8.8

Insulin, mmol/L

31.48 ± 21.2

17.12 ± 12.0*

71.2 ± 73.8

26.43 ± 19.4

16.76 ± 10.9*

70.6 ± 24.7

26.20 ± 6.93

15.21 ± 5.92**

61.3 ± 26.1

HOMA-IR

11.8 ± 9.74

5.3 ± 4.73*

66.1 ± 97.2

10.9 ± 9.14

5.32 ± 3.34**

61.0 ± 29.5

10.8 ± 4.13

5.07 ± 2.89**

47.1 ± 20.5

HbA1c, %

7.1 ± 0.9

5.7 ± 0.70**

72.1 ± 15.1****

7.3 ± 1.0

6.5 ± 0.9**

85.1 ± 8.5

7.0 ± 0.9

6.4 ± 0.6*

89.5 ± 12.5

HbA1c, mmol/mol

53.84 ± 9.6

38.38 ± 7.8**

72.1 ± 15.1****

56.33 ± 10.5

47.93 ± 10.3**

85.1 ± 8.5

52.92 ± 10.1

46.64 ± 6.2*

89.5 ± 12.5

Total cholesterol, mmol/L

4.91 ± 1.03

3.72 ± 0.86**

75.9 ± 9.80***

4.84 ± 0.77

4.73 ± 0.82

97.8 ± 8.7

4.83 ± 0.77

4.54 ± 0.89

94.7 ± 14.9

Triglycerides, mmol/L

1.43 ± 0.66

1.59 ± 0.69

117.6 ± 51.2

1.95 ± 1.39

1.38 ± 0.71

89.2 ± 33.0

1.79 ± 0.75

1.23 ± 0.50

74.0 ± 24.4

HDL cholesterol, mmol/L

1.05 ± 0.21

0.81 ± 0.22**

73.1 ± 22.0****

1.12 ± 0.33

1.15 ± 0.31

104.0 ± 15.1

1.04 ± 0.24

1.08 ± 0.25

105.0 ± 17.3

LDL cholesterol, mmol/L

3.19 ± 1.03

2.23 ± 0.67**

71.4 ± 13.2****

2.82 ± 0.69

2.94 ± 0.77

107.2 ± 25.6

2.96 ± 0.65

2.90 ± 0.82

101.6 ± 33.4

HDL/LDL ratio

0.36 ± 0.14

0.40 ± 0.12

115.3 ± 28.6

0.42 ± 0.17

0.42 ± 0.18

102.0 ± 29.0

0.37 ± 0.11

0.38 ± 0.14

103.6 ± 25.6

  1. Data are means ± standard deviation. Within group statistical significance (pre- to post-surgery) was determined using two-tailed paired t-test or Wilcoxon signed ranks test (*P < 0.05; **P < 0.01), whilst for between group comparisons one-way ANOVA or the Kruskal–Wallis test were used (***P < 0.05; ****P < 0.01)
  2. aDenotes post-surgery values as percentage of pre-surgery values
  3. All serum determinations correspond to fasting status
  4. EWL excess weight loss, BMI body mass index, WHR waist-hip ratio, HOMA-IR Homeostatic assessment model of insulin resistance, HbA1c glycated haemoglobin
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BMC Medicine

ISSN: 1741-7015

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