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Table 1 Anthropometric and metabolic variables pre-surgery and 6 months after biliopancreatic diversion (BPD), laparoscopic greater curvature plication (LGCP) and laparoscopic adjustable gastric banding (LAGB) bariatric procedures

From: Impact of gut hormone FGF-19 on type-2 diabetes and mitochondrial recovery in a prospective study of obese diabetic women undergoing bariatric surgery

  BPD LGCP LAGB
Pre-surgery Post-surgery Change (%) Pre-surgery Post-surgery Change (%) Pre-surgery Post-surgery Change (%)
n 12 15 12
Age, years 50.57 ± 5.88 53.24 ± 7.48 53.57 ± 11.26
EWL, % 30.67 ± 8.42**** 17.36 ± 6.32 20.17 ± 9.36
Body weight, kg 127.7 ± 22.6 106.9 ± 18.5** 83.8 ± 3.0*** 109.2 ± 16.5 97.6 ± 14.1** 89.5 ± 3.2 119.6 ± 19.1 105.3 ± 18.3** 88.1 ± 5.7
BMI, kg/m2 46.45 ± 7.75 39.01 ± 6.37** 84.1 ± 3.5*** 40.41 ± 5.54 36.05 ± 4.62** 89.3 ± 3.4 43.95 ± 6.60 38.31 ± 7.05** 88.90 ± 4.9
WHR, cm 0.93 ± 0.07 0.90 ± 0.07 97.7 ± 9.9 0.88 ± 0.10 0.87 ± 0.08 100.1 ± 11.1 0.90 ± 0.04 0.88 ± 0.04 98.5 ± 5.9
Body fat, % 49.59 ± 3.70 44.68 ± 4.62** 90.2 ± 6.6 48.49 ± 3.78 44.90 ± 3.71** 92.7 ± 4.6 49.54 ± 3.44 46.39 ± 4.45* 93.6 ± 5.6
Glucose, mmol/L 8.40 ± 2.57 7.01 ± 1.73 89.1 ± 30.1 8.93 ± 2.11 7.34 ± 1.64* 84.4 ± 16.9 9.30 ± 2.65 7.07 ± 1.56** 77.4 ± 8.8
Insulin, mmol/L 31.48 ± 21.2 17.12 ± 12.0* 71.2 ± 73.8 26.43 ± 19.4 16.76 ± 10.9* 70.6 ± 24.7 26.20 ± 6.93 15.21 ± 5.92** 61.3 ± 26.1
HOMA-IR 11.8 ± 9.74 5.3 ± 4.73* 66.1 ± 97.2 10.9 ± 9.14 5.32 ± 3.34** 61.0 ± 29.5 10.8 ± 4.13 5.07 ± 2.89** 47.1 ± 20.5
HbA1c, % 7.1 ± 0.9 5.7 ± 0.70** 72.1 ± 15.1**** 7.3 ± 1.0 6.5 ± 0.9** 85.1 ± 8.5 7.0 ± 0.9 6.4 ± 0.6* 89.5 ± 12.5
HbA1c, mmol/mol 53.84 ± 9.6 38.38 ± 7.8** 72.1 ± 15.1**** 56.33 ± 10.5 47.93 ± 10.3** 85.1 ± 8.5 52.92 ± 10.1 46.64 ± 6.2* 89.5 ± 12.5
Total cholesterol, mmol/L 4.91 ± 1.03 3.72 ± 0.86** 75.9 ± 9.80*** 4.84 ± 0.77 4.73 ± 0.82 97.8 ± 8.7 4.83 ± 0.77 4.54 ± 0.89 94.7 ± 14.9
Triglycerides, mmol/L 1.43 ± 0.66 1.59 ± 0.69 117.6 ± 51.2 1.95 ± 1.39 1.38 ± 0.71 89.2 ± 33.0 1.79 ± 0.75 1.23 ± 0.50 74.0 ± 24.4
HDL cholesterol, mmol/L 1.05 ± 0.21 0.81 ± 0.22** 73.1 ± 22.0**** 1.12 ± 0.33 1.15 ± 0.31 104.0 ± 15.1 1.04 ± 0.24 1.08 ± 0.25 105.0 ± 17.3
LDL cholesterol, mmol/L 3.19 ± 1.03 2.23 ± 0.67** 71.4 ± 13.2**** 2.82 ± 0.69 2.94 ± 0.77 107.2 ± 25.6 2.96 ± 0.65 2.90 ± 0.82 101.6 ± 33.4
HDL/LDL ratio 0.36 ± 0.14 0.40 ± 0.12 115.3 ± 28.6 0.42 ± 0.17 0.42 ± 0.18 102.0 ± 29.0 0.37 ± 0.11 0.38 ± 0.14 103.6 ± 25.6
  1. Data are means ± standard deviation. Within group statistical significance (pre- to post-surgery) was determined using two-tailed paired t-test or Wilcoxon signed ranks test (*P < 0.05; **P < 0.01), whilst for between group comparisons one-way ANOVA or the Kruskal–Wallis test were used (***P < 0.05; ****P < 0.01)
  2. aDenotes post-surgery values as percentage of pre-surgery values
  3. All serum determinations correspond to fasting status
  4. EWL excess weight loss, BMI body mass index, WHR waist-hip ratio, HOMA-IR Homeostatic assessment model of insulin resistance, HbA1c glycated haemoglobin