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Table 5 Metabolite differences according to survival rate

From: Metabolomics approaches in pancreatic adenocarcinoma: tumor metabolism profiling predicts clinical outcome of patients

Metabolite No neoadjuvant chemotherapy Mean (nmol/mg) p value
Ascorbate LongSurv 0.3988 ± 0.2221 0.5414
ShortSurv 0.4062 ± 0.2227
Aspartic acid LongSurv 0.6229 ± 0.2255 0.7430
ShortSurv 0.9658 ± 0.6074
Choline LongSurv 0.8849 ± 0.3887 0.0150
ShortSurv 0.9539 ± 0.4702
Creatine LongSurv 1.3561 ± 0.5057 0.2766
ShortSurv 1.4464 ± 0.5971
Ethanolamine LongSurv 0.6148 ± 0.2620 0.0078
ShortSurv 0.7511 ± 0.4177
Glutamate LongSurv 2.4650 ± 0.7699 0.2766
ShortSurv 2.8070 ± 0.9767
Glycerol LongSurv 2.7550 ± 1.1994 0.6730
ShortSurv 3.5300 ± 2.6914
Glycine LongSurv 2.2663 ± 0.8577 0.2359
ShortSurv 2.9025 ± 1.8798
Glycerophosphocholine LongSurv 1.0319 ± 0.5029 0.7430
ShortSurv 1.0810 ± 0.7982
Lactate LongSurv 16.1370 ± 4.7272 0.0360
ShortSurv 15.9030 ± 5.3324
Phosphorylcholine LongSurv 0.9764 ± 0.5008 0.6730
ShortSurv 0.9518 ± 0.4822
Taurine LongSurv 4.4630 ± 1.4062 0.4807
ShortSurv 4.3490 ± 1.3425
Threonine LongSurv 1.1931 ± 0.4229 0.3213
ShortSurv 1.2957 ± 0.6961
Glutamine LongSurv 0.6394 ± 0.2272 0.1672
ShortSurv 0.6870 ± 0.2668
Succinic acid LongSurv 0.1762 ± 0.0763 0.0747
ShortSurv 0.1866 ± 0.0739
Glucose LongSurv 1.3141 ± 1.1020 0.4807
ShortSurv 2.3227 ± 2.7375
Tyrosine LongSurv 0.0730 ± 0.0493 0.0592
ShortSurv 0.1097 ± 0.1479
Phenylalanine LongSurv 0.1789 ± 0.0811 0.0055
ShortSurv 0.1097 ± 0.1958
  1. Results of the Mann-Whitney U test (univariate analysis, nonparametric test). No neoadjuvant chemotherapy. LongSurv long-term survivors, ShortSurv short-term survivors