TY - STD TI - Gorelick PB, et al.; on behalf of the American Heart Association Stroke Council, Council on Epidemiology and Prevention, Council on Cardiovascular Nursing, Council on Cardiovascular Radiology and Intervention, and Council on Cardiovascular Surgery and Anesthesia. Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42:2672–713. ID - ref1 ER - TY - JOUR AU - Bergem, A. L. M. AU - Engedal, K. AU - Kringlen, E. PY - 1997 DA - 1997// TI - The role of heredity in late-onset Alzheimer disease and vascular dementia: a twin study JO - Arch Gen Psychiatry VL - 54 UR - https://doi.org/10.1001/archpsyc.1997.01830150090013 DO - 10.1001/archpsyc.1997.01830150090013 ID - Bergem1997 ER - TY - JOUR AU - Heiss, W. D. AU - Rosenberg, G. A. AU - Thiel, A. AU - Berlot, R. AU - Reuck, J. PY - 2016 DA - 2016// TI - Neuroimaging in vascular cognitive impairment: a state-of-the-art review JO - BMC Med VL - 14 UR - https://doi.org/10.1186/s12916-016-0725-0 DO - 10.1186/s12916-016-0725-0 ID - Heiss2016 ER - TY - JOUR AU - Chabriat, H. AU - Joutel, A. AU - Dichgans, M. AU - Tournier-Lasserve, E. AU - Bousser, M. -. G. PY - 2009 DA - 2009// TI - Cadasil JO - Lancet Neurol VL - 8 UR - https://doi.org/10.1016/S1474-4422(09)70127-9 DO - 10.1016/S1474-4422(09)70127-9 ID - Chabriat2009 ER - TY - JOUR AU - Pastores, G. M. AU - Lien, Y. -. H. H. PY - 2002 DA - 2002// TI - Biochemical and molecular genetic basis of Fabry disease JO - J Am Soc Nephrol VL - 13 ID - Pastores2002 ER - TY - JOUR AU - Clarke, J. T. R. PY - 2007 DA - 2007// TI - Narrative review: Fabry disease JO - An Intern Med VL - 146 UR - https://doi.org/10.7326/0003-4819-146-6-200703200-00007 DO - 10.7326/0003-4819-146-6-200703200-00007 ID - Clarke2007 ER - TY - JOUR AU - Bersano, A. PY - 2012 DA - 2012// TI - Neurological features of Fabry disease: clinical, pathophysiological aspects and therapy JO - Acta Neurol Scand VL - 126 UR - https://doi.org/10.1111/j.1600-0404.2012.01661.x DO - 10.1111/j.1600-0404.2012.01661.x ID - Bersano2012 ER - TY - JOUR AU - Shi, Q. AU - Chen, J. AU - Pongmoragot, J. AU - Lanthier, S. AU - Saposnik, G. PY - 2014 DA - 2014// TI - Prevalence of Fabry disease in stroke patients—a systematic review and meta-analysis JO - J Stroke Cerebrovasc Dis VL - 23 UR - https://doi.org/10.1016/j.jstrokecerebrovasdis.2013.08.010 DO - 10.1016/j.jstrokecerebrovasdis.2013.08.010 ID - Shi2014 ER - TY - JOUR AU - Rolfs, A. PY - 2013 DA - 2013// TI - Acute cerebrovascular disease in the young the stroke in young Fabry patients study JO - Stroke VL - 44 UR - https://doi.org/10.1161/STROKEAHA.112.663708 DO - 10.1161/STROKEAHA.112.663708 ID - Rolfs2013 ER - TY - JOUR AU - Lanfranconi, S. AU - Markus, H. S. PY - 2010 DA - 2010// TI - COL4A1 mutations as a monogenic cause of cerebral small vessel disease a systematic review JO - Stroke VL - 41 UR - https://doi.org/10.1161/STROKEAHA.110.581918 DO - 10.1161/STROKEAHA.110.581918 ID - Lanfranconi2010 ER - TY - JOUR AU - Winkler, D. T. PY - 2008 DA - 2008// TI - Hereditary systemic angiopathy (HSA) with cerebral calcifications, retinopathy, progressive nephropathy, and hepatopathy JO - J Neurol VL - 255 UR - https://doi.org/10.1007/s00415-008-0675-3 DO - 10.1007/s00415-008-0675-3 ID - Winkler2008 ER - TY - JOUR AU - Siveke, J. T. AU - Schmid, H. PY - 2003 DA - 2003// TI - Evidence for systemic manifestations in cerebroretinal vasculopathy JO - Am J Med Genet Part A VL - 123A UR - https://doi.org/10.1002/ajmg.a.20369 DO - 10.1002/ajmg.a.20369 ID - Siveke2003 ER - TY - JOUR AU - Richards, A. PY - 2007 DA - 2007// TI - C-terminal truncations in human 3′-5′ DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy JO - Nat Genet VL - 39 UR - https://doi.org/10.1038/ng2082 DO - 10.1038/ng2082 ID - Richards2007 ER - TY - JOUR AU - Weil, S. PY - 1999 DA - 1999// TI - Cerebroretinal vasculopathy mimicking a brain tumor: a case of a rare hereditary syndrome JO - Neurology VL - 53 UR - https://doi.org/10.1212/WNL.53.3.629 DO - 10.1212/WNL.53.3.629 ID - Weil1999 ER - TY - JOUR AU - DiFrancesco, J. C. PY - 2014 DA - 2014// TI - TREX1 C-terminal frameshift mutations in the systemic variant of retinal vasculopathy with cerebral leukodystrophy JO - Neurol Sci VL - 36 UR - https://doi.org/10.1007/s10072-014-1944-9 DO - 10.1007/s10072-014-1944-9 ID - DiFrancesco2014 ER - TY - JOUR AU - Fukutake, T. PY - 2011 DA - 2011// TI - Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL): from discovery to gene identification JO - J Stroke Cerebrovasc Dis VL - 20 UR - https://doi.org/10.1016/j.jstrokecerebrovasdis.2010.11.008 DO - 10.1016/j.jstrokecerebrovasdis.2010.11.008 ID - Fukutake2011 ER - TY - JOUR AU - Nozaki, H. PY - 2015 DA - 2015// TI - Characteristic features and progression of abnormalities on MRI for CARASIL JO - Neurology VL - 85 UR - https://doi.org/10.1212/WNL.0000000000001803 DO - 10.1212/WNL.0000000000001803 ID - Nozaki2015 ER - TY - JOUR AU - Nozaki, H. AU - Nishizawa, M. AU - Onodera, O. PY - 2014 DA - 2014// TI - Features of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy JO - Stroke VL - 45 UR - https://doi.org/10.1161/STROKEAHA.114.004236 DO - 10.1161/STROKEAHA.114.004236 ID - Nozaki2014 ER - TY - JOUR AU - Cordeiro, I. M. PY - 2015 DA - 2015// TI - Shifting the CARASIL paradigm report of a non-asian family and literature review JO - Stroke VL - 46 UR - https://doi.org/10.1161/STROKEAHA.114.006735 DO - 10.1161/STROKEAHA.114.006735 ID - Cordeiro2015 ER - TY - JOUR AU - Bianchi, S. PY - 2014 DA - 2014// TI - Two novel HTRA1 mutations in a European CARASIL patient JO - Neurology VL - 82 UR - https://doi.org/10.1212/WNL.0000000000000202 DO - 10.1212/WNL.0000000000000202 ID - Bianchi2014 ER - TY - JOUR AU - Tan, R. Y. Y. AU - Markus, H. S. PY - 2015 DA - 2015// TI - Monogenic causes of stroke: now and the future JO - J Neurol VL - 262 UR - https://doi.org/10.1007/s00415-015-7794-4 DO - 10.1007/s00415-015-7794-4 ID - Tan2015 ER - TY - JOUR AU - Bersano, A. PY - 2012 DA - 2012// TI - The genetics of small-vessel disease JO - Curr Med Chem VL - 19 UR - https://doi.org/10.2174/092986712802430081 DO - 10.2174/092986712802430081 ID - Bersano2012 ER - TY - JOUR AU - Yin, Y. -. W. PY - 2012 DA - 2012// TI - Association between apolipoprotein E gene polymorphism and the risk of vascular dementia: a meta-analysis JO - Neurosci Lett VL - 514 UR - https://doi.org/10.1016/j.neulet.2012.02.031 DO - 10.1016/j.neulet.2012.02.031 ID - Yin2012 ER - TY - JOUR AU - Zeng, L. PY - 2015 DA - 2015// TI - Can Chinese herbal medicine adjunctive therapy improve outcomes of senile vascular dementia? Systematic review with meta-analysis of clinical trials JO - Phytother Res VL - 29 UR - https://doi.org/10.1002/ptr.5481 DO - 10.1002/ptr.5481 ID - Zeng2015 ER - TY - JOUR AU - Skrobot, O. A. PY - 2016 DA - 2016// TI - A validation study of vascular cognitive impairment genetics meta-analysis findings in an independent collaborative cohort JO - J Alzheimers Dis VL - 53 UR - https://doi.org/10.3233/JAD-150862 DO - 10.3233/JAD-150862 ID - Skrobot2016 ER - TY - JOUR AU - Alam, R. PY - 2014 DA - 2014// TI - Synergistic epistasis of paraoxonase 1 (rs662 and rs85460) and apolipoprotein E4 genes in pathogenesis of Alzheimer’s disease and vascular dementia JO - Am J Alzheimers Dis Other Demen VL - 29 UR - https://doi.org/10.1177/1533317514539541 DO - 10.1177/1533317514539541 ID - Alam2014 ER - TY - JOUR AU - Dantoine, T. F. PY - 2002 DA - 2002// TI - Paraoxonase 1 192/55 gene polymorphisms in Alzheimer's disease JO - An N Y Acad Sci VL - 977 UR - https://doi.org/10.1111/j.1749-6632.2002.tb04821.x DO - 10.1111/j.1749-6632.2002.tb04821.x ID - Dantoine2002 ER - TY - JOUR AU - Helbecque, N. AU - Cottel, D. AU - Codron, V. AU - Berr, C. AU - Amouyel, P. PY - 2004 DA - 2004// TI - Paraoxonase 1 gene polymorphisms and dementia in humans JO - Neurosci Lett VL - 358 UR - https://doi.org/10.1016/j.neulet.2003.12.100 DO - 10.1016/j.neulet.2003.12.100 ID - Helbecque2004 ER - TY - JOUR AU - Zuliani, G. PY - 2001 DA - 2001// TI - Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia JO - Acta Neurol Scandin VL - 103 UR - https://doi.org/10.1034/j.1600-0404.2001.103005304.x DO - 10.1034/j.1600-0404.2001.103005304.x ID - Zuliani2001 ER - TY - JOUR AU - Bednarska-Makaruk, M. E. PY - 2013 DA - 2013// TI - Paraoxonase 1 (PON1) gene-108C > T and p. Q192R polymorphisms and arylesterase activity of the enzyme in patients with dementia JO - Folia Neuropathol VL - 51 UR - https://doi.org/10.5114/fn.2013.35953 DO - 10.5114/fn.2013.35953 ID - Bednarska-Makaruk2013 ER - TY - JOUR AU - McCusker, S. M. PY - 2001 DA - 2001// TI - Association between polymorphism in regulatory region of gene encoding tumour necrosis factor α and risk of Alzheimer's disease and vascular dementia: a case-control study JO - Lancet VL - 357 UR - https://doi.org/10.1016/S0140-6736(00)04008-3 DO - 10.1016/S0140-6736(00)04008-3 ID - McCusker2001 ER - TY - JOUR AU - Fung, H. C. PY - 2005 DA - 2005// TI - Heat shock protein 70 and tumor necrosis factor alpha in Taiwanese patients with dementia JO - Dement Geriatr Cogn Disord VL - 20 UR - https://doi.org/10.1159/000085067 DO - 10.1159/000085067 ID - Fung2005 ER - TY - JOUR AU - Kim, Y. AU - Lee, C. PY - 2006 DA - 2006// TI - The gene encoding transforming growth factor β1 confers risk of ischemic stroke and vascular dementia JO - Stroke VL - 37 UR - https://doi.org/10.1161/01.STR.0000244782.76917.87 DO - 10.1161/01.STR.0000244782.76917.87 ID - Kim2006 ER - TY - JOUR AU - Peila, R. PY - 2007 DA - 2007// TI - A TGF-β1 polymorphism association with dementia and neuropathologies: the HAAS JO - Neurobiol Aging VL - 28 UR - https://doi.org/10.1016/j.neurobiolaging.2006.06.004 DO - 10.1016/j.neurobiolaging.2006.06.004 ID - Peila2007 ER - TY - JOUR AU - Sun, J. -. H. PY - 2015 DA - 2015// TI - Genetics of vascular dementia: systematic review and meta-analysis JO - J Alzheimers Dis VL - 46 UR - https://doi.org/10.3233/JAD-143102 DO - 10.3233/JAD-143102 ID - Sun2015 ER - TY - JOUR AU - Liu, H. PY - 2010 DA - 2010// TI - The MTHFR C677T polymorphism contributes to an increased risk for vascular dementia: a meta-analysis JO - J Neurol Sci VL - 294 UR - https://doi.org/10.1016/j.jns.2010.04.001 DO - 10.1016/j.jns.2010.04.001 ID - Liu2010 ER - TY - JOUR AU - Dwyer, R. AU - Skrobot, O. A. AU - Dwyer, J. AU - Munafo, M. AU - Kehoe, P. G. PY - 2013 DA - 2013// TI - Using Alzgene-like approaches to investigate susceptibility genes for vascular cognitive impairment JO - J Alzheimers Dis VL - 34 ID - Dwyer2013 ER - TY - JOUR AU - Kim, Y. AU - Kong, M. AU - Lee, C. PY - 2013 DA - 2013// TI - Association of intronic sequence variant in the gene encoding spleen tyrosine kinase with susceptibility to vascular dementia JO - World J Biol Psychiatry VL - 14 UR - https://doi.org/10.3109/15622975.2011.559272 DO - 10.3109/15622975.2011.559272 ID - Kim2013 ER - TY - JOUR AU - Schrijvers, E. M. C. PY - 2012 DA - 2012// TI - Genome-wide association study of vascular dementia JO - Stroke VL - 43 UR - https://doi.org/10.1161/STROKEAHA.111.628768 DO - 10.1161/STROKEAHA.111.628768 ID - Schrijvers2012 ER - TY - JOUR AU - Ikram, M. A. PY - 2009 DA - 2009// TI - Genomewide association studies of stroke JO - New Engl J Med VL - 360 UR - https://doi.org/10.1056/NEJMoa0900094 DO - 10.1056/NEJMoa0900094 ID - Ikram2009 ER - TY - JOUR PY - 2016 DA - 2016// TI - Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies JO - Lancet Neurol VL - 15 UR - https://doi.org/10.1016/S1474-4422(16)00102-2 DO - 10.1016/S1474-4422(16)00102-2 ID - ref41 ER - TY - JOUR AU - Bellenguez, C. PY - 2012 DA - 2012// TI - Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke JO - Nat Genet VL - 44 UR - https://doi.org/10.1038/ng.1081 DO - 10.1038/ng.1081 ID - Bellenguez2012 ER - TY - STD TI - NINDS Stroke Genetics Network (SiGN).; International Stroke Genetics Consortium (ISGC). Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. Lancet Neurol. 2015. http://www.thelancet.com/journals/laneur/article/PIIS1474-4422(15)00338-5/abstract. UR - http://www.thelancet.com/journals/laneur/article/PIIS1474-4422(15)00338-5/abstract ID - ref43 ER - TY - JOUR AU - Lambert, J. -. C. PY - 2013 DA - 2013// TI - Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JO - Nat Genet VL - 45 UR - https://doi.org/10.1038/ng.2802 DO - 10.1038/ng.2802 ID - Lambert2013 ER - TY - JOUR AU - Karch, C. M. AU - Goate, A. M. PY - 2015 DA - 2015// TI - Alzheimer’s disease risk genes and mechanisms of disease pathogenesis JO - Biol Psychiatr VL - 77 UR - https://doi.org/10.1016/j.biopsych.2014.05.006 DO - 10.1016/j.biopsych.2014.05.006 ID - Karch2015 ER - TY - JOUR AU - Verhaaren, B. F. J. PY - 2015 DA - 2015// TI - Multi-ethnic genome-wide association study of cerebral white matter hyperintensities on MRI JO - Circ Cardiovasc Genet VL - 8 UR - https://doi.org/10.1161/CIRCGENETICS.114.000858 DO - 10.1161/CIRCGENETICS.114.000858 ID - Verhaaren2015 ER - TY - JOUR AU - Verhaaren, B. F. J. PY - 2011 DA - 2011// TI - Replication study of chr17q25 with cerebral white matter lesion volume JO - Stroke VL - 42 UR - https://doi.org/10.1161/STROKEAHA.111.623090 DO - 10.1161/STROKEAHA.111.623090 ID - Verhaaren2011 ER - TY - JOUR AU - Tabara, Y. PY - 2013 DA - 2013// TI - Association of Chr17q25 with cerebral white matter hyperintensities and cognitive impairment: the J‐SHIPP study JO - Eur J Neurol VL - 20 UR - https://doi.org/10.1111/j.1468-1331.2012.03879.x DO - 10.1111/j.1468-1331.2012.03879.x ID - Tabara2013 ER - TY - JOUR AU - Traylor, M. PY - 2016 DA - 2016// TI - Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke JO - Neurology VL - 86 UR - https://doi.org/10.1212/WNL.0000000000002263 DO - 10.1212/WNL.0000000000002263 ID - Traylor2016 ER - TY - JOUR AU - Hofer, E. PY - 2015 DA - 2015// TI - White matter lesion progression genome-wide search for genetic influences JO - Stroke VL - 46 UR - https://doi.org/10.1161/STROKEAHA.115.009252 DO - 10.1161/STROKEAHA.115.009252 ID - Hofer2015 ER - TY - JOUR AU - Debette, S. PY - 2010 DA - 2010// TI - Genome-wide association studies of MRI-defined brain infarcts meta-analysis from the CHARGE consortium JO - Stroke VL - 41 UR - https://doi.org/10.1161/STROKEAHA.109.569194 DO - 10.1161/STROKEAHA.109.569194 ID - Debette2010 ER - TY - JOUR AU - Bulik-Sullivan, B. K. PY - 2015 DA - 2015// TI - LD Score regression distinguishes confounding from polygenicity in genome-wide association studies JO - Nat Genet VL - 47 UR - https://doi.org/10.1038/ng.3211 DO - 10.1038/ng.3211 ID - Bulik-Sullivan2015 ER - TY - JOUR AU - Bersano, A. PY - 2015 DA - 2015// TI - Next generation sequencing for systematic assessment of genetics of small-vessel disease and lacunar stroke JO - J Stroke Cerebrovasc Dis VL - 24 UR - https://doi.org/10.1016/j.jstrokecerebrovasdis.2014.10.019 DO - 10.1016/j.jstrokecerebrovasdis.2014.10.019 ID - Bersano2015 ER - TY - JOUR AU - Perneczky, R. PY - 2016 DA - 2016// TI - Is the time ripe for new diagnostic criteria of cognitive impairment due to cerebrovascular disease? Consensus report of the International Congress on Vascular Dementia working group JO - BMC Med VL - 14 UR - https://doi.org/10.1186/s12916-016-0719-y DO - 10.1186/s12916-016-0719-y ID - Perneczky2016 ER - TY - JOUR AU - Akoudad, S. PY - 2014 DA - 2014// TI - Cerebral microbleeds are associated with the progression of ischemic vascular lesions JO - Cerebrovasc Dis VL - 37 UR - https://doi.org/10.1159/000362590 DO - 10.1159/000362590 ID - Akoudad2014 ER - TY - JOUR AU - Charidimou, A. PY - 2013 DA - 2013// TI - Enlarged perivascular spaces as a marker of underlying arteriopathy in intracerebral haemorrhage: a multicentre MRI cohort study JO - J Neurol Neurosurg Psychiatry VL - 84 UR - https://doi.org/10.1136/jnnp-2012-304434 DO - 10.1136/jnnp-2012-304434 ID - Charidimou2013 ER - TY - JOUR AU - Groot, M. PY - 2013 DA - 2013// TI - Changes in normal-appearing white matter precede development of white matter lesions JO - Stroke VL - 44 UR - https://doi.org/10.1161/STROKEAHA.112.680223 DO - 10.1161/STROKEAHA.112.680223 ID - Groot2013 ER - TY - JOUR AU - Hachinski, V. PY - 2006 DA - 2006// TI - National Institute of Neurological Disorders and Stroke–Canadian stroke network vascular cognitive impairment harmonization standards JO - Stroke VL - 37 UR - https://doi.org/10.1161/01.STR.0000237236.88823.47 DO - 10.1161/01.STR.0000237236.88823.47 ID - Hachinski2006 ER - TY - JOUR AU - Roses, A. D. PY - 2010 DA - 2010// TI - A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease JO - Pharmacogenom J VL - 10 UR - https://doi.org/10.1038/tpj.2009.69 DO - 10.1038/tpj.2009.69 ID - Roses2010 ER - TY - JOUR AU - Roses, A. D. PY - 2014 DA - 2014// TI - New applications of disease genetics and pharmacogenetics to drug development JO - Curr Opin Pharmacol VL - 14 UR - https://doi.org/10.1016/j.coph.2013.12.002 DO - 10.1016/j.coph.2013.12.002 ID - Roses2014 ER - TY - JOUR AU - McCarthy, A. D. AU - Kennedy, J. L. AU - Middleton, L. T. PY - 2005 DA - 2005// TI - Pharmacogenetics in drug development JO - Philosoph Trans Royal Soc B VL - 360 UR - https://doi.org/10.1098/rstb.2005.1688 DO - 10.1098/rstb.2005.1688 ID - McCarthy2005 ER -