Table 1 Characteristics of all patients stratified according to tuberculosis status
|  | All patients (n = 427) | Patients with a TB diagnosis (n = 139) | Patients without a TB diagnosis (n = 288) | P value |
|---|---|---|---|---|
Age (years), median (IQR) | 36.1 (28.9–42.4) | 33.8 (27.2–39.7) | 37.1 (30.0–44.0) | 0.008 |
Female | 259 (60.7) | 90 (64.8) | 169 (58.7) | 0.229 |
New HIV diagnosis on admission | 82 (19.2) | 34 (24.5) | 48 (16.7) | 0.055 |
TB characteristics | ||||
 History of previous TB* | 196 (46.1) | 50 (36.2) | 146 (50.9) | 0.005 |
 RIF resistance | 4 (0.9) | 4 (2.9) | 0 | 0.004 |
ART status | ||||
 ART-naive | 177 (41.5) | 71 (51.1) | 106 (36.8) | 0.019 |
 ART interrupted | 71 (16.6) | 19 (13.7) | 52 (18.1) |  |
 Current ART use | 179 (41.9) | 49 (35.3) | 130 (45.1) |  |
 Treatment duration if currently on ART (years), median (IQR)a | 1.6 (0.6–3.6) | 1.3 (0.2–2.9) | 1.7 (0.6–3.7) | 0.157 |
CD4 counts (cells/μL)* | ||||
 Median (IQR) | 149 (55–312) | 80 (33–182) | 191 (73–392) | <0.001 |
 <50 | 94 (22.2) | 53 (38.4) | 41 (14.3) |  |
 50–99 | 66 (15.6) | 21 (15.2) | 45 (15.7) |  |
 100–149 | 54 (12.7) | 19 (13.8) | 35 (12.2) |  |
 150–199 | 42 (9.9) | 16 (11.6) | 26 (9.1) |  |
 ≥200 | 169 (39.9) | 29 (21.0) | 140 (49.0) |  |
HIV viral load (log copies/mL)b | ||||
 Median (IQR) | 4.4 (1.6–5.5) | 5.1 (3.3–5.8) | 4.0 (1.6–5.4) | <0.001 |
 Virally suppressed (<400 copies/mL) | 131 (31.6) | 25 (19.8) | 106 (36.8) | 0.001 |
Haemoglobin levels* | ||||
 Median (IQR) | 9.6 (7.7–11.6) | 8.4 (6.8–10.2) | 10.2 (8.2–12.2) | <0.001 |
 No/mild anaemia | 144 (34.2) | 28 (20.1) | 116 (41.1) |  |
 Moderate/severe anaemia | 277 (65.8) | 111 (79.9) | 166 (58.9) |  |
C-reactive protein (mg/L)c | ||||
 Median (IQR) | 73 (17–153) | 112 (70–182) | 54 (12–135) | <0.001 |
 >50 | 246 (61.2) | 108 (82.4) | 138 (50.9) | <0.001 |
Symptoms | ||||
 Cough ≥2 weeks* | 34 (8.0) | 18 (13.0) | 16 (5.6) | 0.008 |
 Sputum production* | 161 (38.3) | 51 (37.5) | 110 (38.7) | 0.808 |
 Current cough* | 201 (47.4) | 84 (60.9) | 117 (40.9) | <0.001 |
 Current fever* | 63 (14.9) | 24 (17.5) | 39 (13.6) | 0.294 |
 Current night sweats* | 174 (41.0) | 73 (52.9) | 101 (35.3) | 0.001 |
 Current reported weight loss* | 189 (44.5) | 76 (55.1) | 113 (39.4) | 0.002 |
 Positive WHO symptoms screen* | 389 (91.5) | 134 (97.1) | 255 (88.9) | 0.005 |