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Table 4 Association between characteristics of patients with tuberculosis (n = 136) and detection of lipoarabinomannan in urine

From: Diagnostic accuracy, incremental yield and prognostic value of Determine TB-LAM for routine diagnostic testing for tuberculosis in HIV-infected patients requiring acute hospital admission in South Africa: a prospective cohort

 

Unadjusted odds ratio

(95% CI)

Log-rank

Adjusted odds ratio

(95% CI)

Log-rank

Age (for each year decrease)

1.01 (0.98–1.05)

0.491

  

Gender

 Female

1.00

0.154

  

 Male

1.68 (0.82–3.43)

   

ART status

 Any ART exposure

1.00

0.748

  

 ART naive

1.12 (0.56–2.24)

   

History of previous TB

 Yes

1.0

0.496

  

 No

1.29 (0.62–2.67)

   

CD4 category (cells/uL)

 ≥150

1.00

<0.001

1.00

0.002

 100–149

4.55 (1.22–16.98)

 

4.37 (1.12–16.98)

 

 50–99

9.53 (2.64–34.35)

 

6.76 (1.78–25.65)

 

 <50

10.64 (3.61–31.36)

 

7.20 (2.34–22.17)

 

Anaemia category

 None/mild

1.00

<0.001

1.00

0.051

 Moderate

4.00 (1.03–15.44)

 

2.41 (0.57–10.24)

 

 Severe

9.66 (2.64–35.33)

 

4.62 (1.14–18.74)

 

Self-reported sputum production

 No

1.00

0.264

  

 Yes

1.51 (0.73–3.13)

   

Sputum produced in the first 24 hours

 Yes

1.00

0.841

  

 No

1.08 (0.52–2.25)

   

Sputum sample produced during study admission

 Yes

1.00

0.749

  

 No

1.13 (0.54–2.35)

   

WHO screen positive

 No

1.00

0.541

  

 Yes

1.97 (0.20–19.50)

   
  1. Abbreviations: ART antiretroviral therapy, CI confidence interval, TB tuberculosis, WHO World Health Organization