Skip to main content

Table 2 Mean (95% CI) anti-LPS and anti-flagellin immunoglobulin levels in controls by sex, age at blood collection, and other baseline characteristics

From: Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested case-control study

Characteristic

Anti-LPS IgG + IgA

95% CI

Anti-Flagellin IgG + IgA

95% CI

Anti-LPS IgG + Anti-Flagellin IgG

95% CI

Anti-LPS IgA + Anti-Flagellin IgA

95% CI

Anti-LPS IgG + IgA + Anti-Flagellin IgG + IgA

95% CI

Sex

 Female

3.78

3.37

4.19

3.18

2.82

3.54

3.37

3.00

3.74

3.59

3.15

4.02

6.96

6.23

7.68

 Male

3.58

3.32

3.85

3.24

3.01

3.48

3.11

2.88

3.35

3.71

3.43

3.99

6.82

6.35

7.29

P value*

0.425

  

0.771

  

0.249

  

0.639

  

0.762

  

Age at blood collection, years

 ≤55

3.64

3.21

4.07

3.11

2.72

3.49

3.26

2.87

3.65

3.48

3.02

3.94

6.75

5.97

7.52

 55.1–60

3.40

2.93

3.87

3.24

2.82

3.66

2.99

2.57

3.42

3.64

3.15

4.14

6.64

5.80

7.47

 60.1–65

3.56

3.15

3.96

3.13

2.77

3.48

3.10

2.73

3.46

3.58

3.16

4.01

6.68

5.96

7.40

 >65

4.01

3.53

4.48

3.48

3.06

3.90

3.44

3.01

3.86

4.05

3.55

4.56

7.49

6.64

8.34

P value*

0.218

  

0.270

  

0.499

  

0.131

  

0.215

  

BMI, kg/m2

 ≤25

3.39

2.98

3.79

3.02

2.65

3.38

3.04

2.68

3.40

3.37

2.93

3.80

6.41

5.68

7.13

 25.1–29.9

3.55

3.23

3.87

3.24

2.95

3.52

3.03

2.75

3.32

3.75

3.41

4.09

6.78

6.21

7.35

 ≥30

4.11

3.67

4.55

3.44

3.04

3.83

3.67

3.28

4.06

3.88

3.41

4.35

7.55

6.76

8.34

P value*

0.019

  

0.123

  

0.022

  

0.114

  

0.036

  

Waist-to-hip ratio (WHR)

 <0.92 (M)/<0.77 (W)

3.35

2.98

3.73

3.15

2.81

3.49

2.98

2.64

3.32

3.53

3.12

3.93

6.50

5.83

7.18

 0.92–0.97 (M)/0.77–0.84 (W)

3.77

3.41

4.14

3.21

2.89

3.54

3.27

2.93

3.60

3.72

3.33

4.11

6.99

6.33

7.64

 >0.97 (M)/>0.84 (W)

3.80

3.40

4.20

3.31

2.96

3.67

3.34

2.98

3.70

3.78

3.35

4.21

7.12

6.40

7.83

P value*

0.110

  

0.510

  

0.153

  

0.401

  

0.221

  

CRP, mg/L

 ≤1

3.40

3.03

3.76

3.09

2.75

3.42

3.02

2.69

3.36

3.46

3.06

3.86

6.48

5.82

7.14

 1–5

3.68

3.25

4.12

3.39

2.99

3.78

3.27

2.88

3.66

3.80

3.33

4.27

7.07

6.29

7.85

 >5

3.95

3.36

4.53

3.33

2.80

3.86

3.17

2.65

3.70

4.10

3.47

4.74

7.28

6.23

8.32

P valuea

0.098

  

0.326

  

0.493

  

0.077

  

0.156

  
  1. *All P values are based on a test of linear trend, except P values for heterogeneity by sex, smoking status, and lifetime alcohol drinking pattern
  2. aAvailable for 100 controls