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Table 2 Difference of LDL-C estimates relative to direct ultracentrifugation by LDL-C and TG categories

From: Accuracy of low-density lipoprotein cholesterol estimation at very low levels

  Overall population TG < 150 mg/dL TG 150–199 mg/dL TG 200–399 mg/dL
Estimated LDL-C (mg/dL) LDLf-C LDLn-C LDLf-C LDLn-C LDLf-C LDLn-C LDLf-C LDLn-C
< 15 –29.0 –37.4 to –19.6 –2.7 –4.9 to 0.0 –3.8 –6.8 to 0.0 –1.5 –3.2 to 0.4 –15.0 –17.2 to –11.4 –8.2 –9.6 to –5.8 –32.5 –39.0 to –25.6 –10.8 –15.3 to –6.9
15 to < 25 –16.2 –26.8 to –5.8 –1.8 –3.5 to –0.3 –2.8 –6.0 to 0.4 –1.5 –2.7 to 0.0 –13.0 –15.4 to –10.6 –4.6 –7.0 to –1.3 –26.1 –33.2 to –20.4 –6.7 –10.3 to –3.3
25 to < 40 –7.0 –16.2 to –1.2 –1.1 –2.5 to 0.3 –1.6 –4.8 to 0.8 –1.0 –2.2 to 0.3 –11.0 –13.6 to –8.2 –2.7 –4.9 to –0.3 –21.8 –28.8 to –16.6 –3.2 –7.0 to 0.4
40 to < 50 –4.0 –10.6 to –0.2 –0.7 –2.0 to 0.7 –1.2 –4.0 to 1.2 –0.7 –1.9 to 0.6 –9.8 –12.4 to –7.2 –1.1 –3.3 to 1.3 –19.4 –25.4 to –14.6 –1.4 –4.7 to 2.1
50 to < 70 –2.4 –7.4 to 0.6 –0.1 –1.5 to 1.3 –0.6 –3.2 to 1.4 –0.2 –1.4 to 1.1 –8.6 –11 to –6.0 0.0 –2.1 to 2.6 –17.0 –22.6 to –12.4 –0.2 –3.8 to 3.6
Total –2.8 –8.6 to 0.4 –0.3 –1.7 to 1.1 –0.8 –3.4 to 1.4 –0.3 –1.5 to 1.0 –9.0 –11.6 to –6.2 –0.3 –2.4 to 2.3 –18.4 –24.6 to –13.6) –0.5 –4.1 to 3.3
  1. Differences reported as median above with 25th to 75th percentiles below, in mg/dL. Differences were calculated as: LDLf-C – LDLd-C, and LDLn-C – LDLd-C; thus, negative values indicate underestimation and vice versa. Numbers of individuals per LDL-C category are the same as in Table 1