Table 1 Selected baseline characteristics of comparative randomized controlled trials and matched observational studies
Trial | Year | Age, years | Male, % | Diabetes, % | Hypertension, % | Dyslipidemia, % | Current smoker, % | Prior PCI, % | Prior MI, % | No. | FU, years | EF, % | Study period | Adjusting method |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LE MANS [24] | 2016 | 61.3 ± 8.4 | 73 | 17 | 70 | 60 | NA | NA | 33 | 105 | 10 | 53.7 ± 6.7 | 2001–2004 | Randomization |
PRECOMBAT [10] | 2015 | 62.7 ± 9.5 | 77 | 30 | 51.3 | 40 | 27.7 | 12.7 | 6.7 | 600 | 5 | 60.8 ± 8.5 | 2004–2009 | Randomization |
SYNTAX [11] | 2014 | 65.6 ± 10.1 | 75.6 | 25.6 | 62.4 | 75.4 | 24 | NA | 25.4 | 705 | 5 | NA | 2005–2007 | Randomization |
Boudriot et al. [23] | 2011 | 69 (63–73) | 77 | 33 | 82 | 64 | 28 | NA | 14 | 201 | 5 | 65 (55–68) | 2003–2009 | Randomization |
EXCEL [12] | 2016 | 65.9 ± 9.5 | 77.5 | 28 | 73.9 | 69.3 | 20.8 | 15.9 | 16.9 | 1905 | 3 | 57.3 ± 9.0 | 2010–2014 | Randomization |
NOBLE [13] | 2016 | 66.2 ± 9.4 | 76 | 15 | 66 | 78 | 22 | 20 | NA | 1184 | 5 | 60 (52–64) | 2008–2015 | Randomization |
Zheng et al. [14] | 2016 | 62.2 ± 9.1 | 82 | 31 | 64.3 | 59.1 | 53.6 | 9.7 | 38.1 | 4046 | 3 | 60.2 ± 8.2 | 2004–2010 | Propensity score adjustment |
Yu et al. [33] | 2016 | 64 (57–70) | 82.5 | 28.7 | 58.9 | 34.6 | 44.9 | 6.8 | 21.7 | 922 | 7.1 | 62 (54–68) | 2003–2009 | Propensity score adjustment |
Lu et al. [32] | 2016 | 69 ± 11 | 85.5 | 46 | 83 | 50 | 67 | NA | NA | 478 | 4.3 | 49 ± 12 | 2004–2010 | Propensity score adjustment |
Wei et al. [41] | 2016 | 71.0 ± 5.9 | 79 | 45.2 | 72.6 | 21.0 | 58.1 | NA | NA | 126 | 1.3 | 48.8 ± 7.5 | 2012–2013 | Multivariate adjusted |
IRIS-MAIN registry-1 [15] | 2016 | 61 ± 10 | 75.3 | 31.5 | 51.8 | 33.4 | 33.1 | 10.8 | 15.5 | 954 | 9.7 | 58 ± 11 | 1995–2002 | Multivariate adjusted |
IRIS-MAIN registry-2 [15] | 2016 | 64 ± 9 | 74.4 | 38.4 | 54.8 | 34.6 | 27.2 | 12.3 | 13.3 | 1901 | 5.6 | 56 ± 11 | 2003–2006 | Multivariate adjusted |
IRIS-MAIN registry-3 [15] | 2016 | 65 ± 9 | 79.1 | 42.5 | 65.9 | 50.3 | 25.9 | 13.4 | 12.2 | 2362 | 3 | 55 ± 11 | 2007–2013 | Multivariate adjusted |
Jeong et al. [28] | 2013 | 60.8 ± 10 | 79.2 | 30.8 | 49.1 | 1.7 | 20.1 | 18.2 | 6.9 | 318 | 4.7 | NA | 2001–2009 | Propensity matching |
DELTA registry [16] | 2012 | 66.8 ± 10.5 | 65 | 31.6 | 68.1 | 65.6 | 43 | 16.8 | NA | 1204 | 3.5 | 53.2 ± 11.4 | 2002–2006 | Propensity matching |
CREDO-Kyoto 2 [40] | 2012 | 69.4 ± 9.2 | 77 | 45 | 85 | NA | 25 | NA | 16 | 1005 | 3 | 60.2 ± 13.4 | 2005–2007 | Multivariate adjusted |
Chang et al. [27] | 2012 | 64 ± 8.7 | 72.6 | 35.8 | 53.2 | 33.2 | 26.3 | 14.7 | 12.6 | 380 | 4.2 | 40.1 ± 27.8 | 2003–2009 | Propensity matching |
Yi et al. [29] | 2012 | 64.2 ± 8.3 | 82.7 | 31.3 | 62.5 | NA | NA | NA | NA | 256 | 5 | NA | 2003–2007 | Propensity matching |
CUSTOMIZE registry [25] | 2011 | 65.3 ± 10.5 | 76.3 | 33.5 | 68.2 | 54.3 | 48 | 22 | 31.2 | 346 | 3 | 52.1 ± 9.0 | 2002–2011 | Propensity matching |
Rittger et al. [34] | 2011 | 65 ± 7 | 78 | 45 | 84 | 94 | NA | 22 | 18 | 286 | 1 | 55 ± 14 | 2004–2007 | Propensity score adjustment |
Asan-Multivessel Registry [31] | 2011 | NA | NA | NA | NA | NA | NA | NA | NA | 550 | 5.6 | NA | 2003–2005 | Propensity score adjustment |
Kang et al. [30] | 2010 | 64.3 ± 10.3 | 71.4 | 41.9 | 67.6 | 52.4 | 48.6 | NA | NA | 210 | 2.8 | 53.7 ± 13.1 | 2003–2006 | Propensity matching |
Mäkikallio et al. [39] | 2009 | 70 ± 9 | 80 | 17 | 46 | NA | 18 | 3 | NA | 287 | 1 | 54 ± 11 | 2005–2007 | Multivariate adjusted |
MAIN-COMPARE registry [26] | 2008 | 64 (56–70) | 71.2 | 33 | 50 | 30.1 | 27.1 | 15.1 | 10 | 1084 | 3 | 61 (55–66) | 2000–2006 | Propensity matching |
Ghenim et al. [35] | 2009 | 79.6 ± 3.5 | 71.7 | 23.6 | 65.1 | 41.5 | 24.5 | 20.7 | 19.8 | 211 | 1 | NA | 2004–2006 | Propensity score adjustment |
White et al. [36] | 2008 | 69.4 ± 1.7 | 77 | 27 | 76 | 77 | 17 | NA | NA | 353 | 2 | 54 ± 11 | 2003–2007 | Propensity score adjustment |
Rodes-Cabau et al. [37] | 2008 | 82 ± 2 | 63 | 26 | 72 | 82 | 6 | 8 | 59 | 249 | 2 | 56 ± 14 | 2002–2008 | Propensity score adjustment |
Palmerini et al. [38] | 2007 | 78 (75–88) | 66 | 26 | 73 | 47 | 39 | NA | NA | 259 | 2 | 53 (25–78) | 2003–2006 | Propensity score adjustment |