Skip to main content

Table 2 Stratified analysis of each endpoint based on study design, duration of follow-up, and stent type

From: Percutaneous intervention versus coronary artery bypass graft surgery in left main coronary artery stenosis: a systematic review and meta-analysis

Endpoint

Subgroup

No. of study

HR

95% LCI

95% UCI

P value

I 2

P_heterogeneity

P_interaction

All-cause death

Randomized trial

5

1.00

0.79

1.26

0.97

22.3

0.27

0.57

 

Matched study

17

1.08

0.92

1.26

0.36

36.5

0.07

 
 

Long-term

17

1.05

0.92

1.20

0.44

35

0.08

0.93

 

Midterm

5

1.02

0.6

1.74

0.95

37.1

0.17

 
 

Second-generation DES

3

1.05

0.78

1.42

0.75

47.7

0.15

0.99

 

BMS or early-generation DES

19

1.05

0.91

1.22

0.50

33.3

0.08

 

Cardiac death

Randomized trial

4

1.00

0.72

1.39

0.99

20.5

0.29

0.62

 

Matched study

5

1.08

0.51

2.29

0.83

77.9

0.001

 
 

Long term

8

1.09

0.72

1.65

0.67

73.1

< 0.001

0.31

 

Mid term

1

0.28

0.03

2.70

0.27

NA

NA

 
 

Second-generation DES

2

1.10

0.75

1.63

0.63

0

0.59

0.97

 

BMS or early-generation DES

7

1.01

0.58

1.77

0.97

77.2

< 0.001

 

MI

Randomized trial

5

1.39

0.85

2.27

0.19

57.5

0.05

0.18

 

Matched study

5

2.01

1.64

2.45

< 0.001

0

0.72

 
 

Long term

10

1.69

1.22

2.24

0.002

57.7

0.01

NA

 

Mid term

0

NA

NA

NA

NA

NA

NA

 
 

Second-generation DES

2

1.56

0.52

4.71

0.43

87.3

0.005

0.39

 

BMS or early-generation DES

8

1.92

1.59

2.31

< 0.001

0

0.73

 

Stroke

Randomized trial

5

0.84

0.47

1.50

0.56

50.9

0.09

0.25

 

Matched study

4

0.44

0.18

1.07

0.07

79.4

0.002

 
 

Long term

9

0.64

0.33

1.24

0.19

83.5

< 0.001

NA

 

Mid term

0

NA

NA

NA

NA

NA

NA

 
 

Second-generation DES

2

1.25

0.44

3.54

0.68

74.6

0.05

0.15

 

BMS or early-generation DES

7

0.48

0.25

0.93

0.03

74.2

0.001

 

Revascularization

Randomized trial

5

1.68

1.40

2.02

< 0.001

0

0.53

0.10

 

Matched study

15

3.52

2.07

5.99

< 0.001

93.8

< 0.001

 
 

Long term

18

2.57

1.68

4.92

< 0.001

93.5

< 0.001

0.17

 

Mid term

2

8.69

3.33

22.69

< 0.001

0

0.93

 
 

Second-generation DES

3

2.26

1.23

4.15

0.008

86.2

0.001

0.72

 

BMS or early-generation DES

17

2.92

1.80

4.75

< 0.001

93.4

< 0.001

 

Death/MI/stroke

Randomized trial

3

0.96

0.80

1.15

0.66

0

0.86

0.43

 

Matched study

14

1.10

0.99

1.22

0.08

39.5

0.06

 
 

Long term

14

1.07

0.97

1.17

0.16

36.4

0.09

0.48

 

Mid term

3

0.89

0.58

1.38

0.61

11.9

0.32

 
 

Second-generation DES

2

0.96

0.80

1.15

0.69

0

0.62

0.52

 

BMS or early-generation DES

15

1.10

0.99

1.22

0.09

35.3

0.09

 

MACCE

Randomized trial

5

1.20

1.00

1.44

0.05

44.6

0.13

0.31

 

Matched study

11

1.57

1.14

2.17

0.006

87.7

< 0.001

 
 

Long term

12

1.50

1.18

1.91

0.001

86.7

< 0.001

0.39

 

Mid term

4

1.07

0.52

2.19

0.86

80.2

0.002

 
 

Second-generation DES

3

1.35

1.15

1.59

< 0.001

28.6

0.25

0.93

 

BMS or early-generation DES

13

1.42

1.05

1.92

0.02

87.3

< 0.001

 
  1. BMS bare-metal stent, DES drug-eluting stent, HR hazard ratio, LCI lower 95% confidence interval, MACCE major adverse cardiac and cerebrovascular event, MI myocardial infarction, NA not applicable, UCI upper 95% confidence interval
Back to article page

BMC Medicine

ISSN: 1741-7015

Contact us