Table 1 Top genes that were verified using bisulfite pyrosequencing
Rank | Gene symbol | Gene Name | Total CpGs analyzed | Significant CpGs* Discovery Validation | Presence of CpG island | Correlation with mRNA expression | |
|---|---|---|---|---|---|---|---|
(Set 1) | (Set 3) | ||||||
1 | FZD10 | Frizzled-homologue 10 (CD350 antigen) | 8 | 5 | 4 | Yes | Inverse |
2 | FAM83A | Family with sequence similarity 83, Member A (Tumor Antigen BJ-TSA-9) | 7 | 5 | 4 | No | Inverse |
3 | MYO18B | Myosin-XVIIIb | 3 | 3 | 2 | No | Inverse |
4 | MKX | Homeobox protein Mohawk | 4 | 4 | 1 | Yes | Inverse |
5 | GLI3 | GLI Family Zinc Finger 3 | 6 | 5 | 0 | Yes | Direct |
6 | TMIGD2 | Transmembrane and immunoglobulin domain-containing 2 (CD28 homologue) | 5 | 4 | 0 | No | Direct |
7 | TMEM40 | Transmembrane protein 40 | 6 | 6 | 0 | No | Direct |
8 | NEUROG3 | Neurogenin-3 | 16 | 13 | 0 | Yes | Inverse |
9 | HOMER3 | Homer protein homolog 3 | 7 | 6 | 0 | No | Direct |