Fig. 1

Influence of uricosuric agents lesinurad (L), benzbromarone (B) and probenecid (P) on the activity of renal uric acid transporters. Bold text, strong effect; normal text, weak to moderate effect; strikethrough, no effect; no text, no data were found. Based on information and data from [71–80]. OAT organic anion transporter; URAT1 urate transporter 1; NPT sodium phosphate transporter. Adapted with permission from Dalbeth et al. [81]