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Table 1 Overview of model parameters

From: Assessing the efficiency of catch-up campaigns for the introduction of pneumococcal conjugate vaccine: a modelling study based on data from PCV10 introduction in Kilifi, Kenya

Model parameters   Contribution No. of parameters Prior Posterior
     Distribution Mean SD Source Median CR
Study population Age group size Fixed 6 age groups KHDSS [4]
  Contact patterns Fixed 6 × 6 age groups KHDSS [5]
Carriage prevalence Outcome 2 types × 6 age groups KHDSS [11]
IPD Outcome 2 types × 6 age groups KHDSS [12]
Observed vaccine coverage Fixed 27,040 (weekly age and time) KHDSS [4]
Transmission dynamics Clearance rates Fixed 2 types × 4 age groups     KHDSS [15]   
  VE carriage (toddlers) Fitted - prior 1 Normal 0.36 0.15 KHDSS [11] 0.56 0.41–0.72
VE IPD (infants) Fitted - prior 1 Normal 0.80 0.1 [22] 0.86 0.67–0.99
Duration of protection (toddlers) Fitted - prior 1 Normal 6 years 3 [23, 24] 5.50 2.05–11.01
Relative level of infant protection Fitted - prior 1 Normal 1 0.1 Assumption 0.97 0.78–1.17
Competition parameter Fitted - prior 1 Log-normal 0.15 0.15 [17, 18] 0.19 0.07–0.44
Susceptibility to infection Fitted - no prior 2 types × 4 age groups       
Invasiveness Fitted - no prior 2 types × 4 age groups      
  1. CR Credible range, VE Vaccine efficacy