The clinical utility of the urine-based lateral flow lipoarabinomannan assay in HIV-infected adults in Myanmar: an observational study

Table 2 Characteristics of the patients who died during follow-up

Age, Gender	CD4 T-cell count^a	On ART^a	On IPT^a	Initial enrolment	LF-LAM result^a	TB symptoms^b	Anti-TB therapy before death^c	Time of death^d	Cause of death^e
23, Female	56	Yes	No	Inpatient	Positive grade 3	Yes	Empirical	3 days	Suspected TB meningitis
32, Female	59	No	No	Inpatient	Positive grade 2	Yes	Directed	29 days	Confirmed TB meningitis
28, Female	14	No	No	Inpatient	Positive grade 3	Yes	Directed	34 days	Confirmed miliary TB
28, Female	144	Yes	No	Inpatient	Positive grade 4	Yes	No	87 days	Confirmed cryptococcal meningitis
33, Female	61	No	No	Inpatient	Negative	Yes	No	131 days	Suspected Pneumocystis jirovecii pneumonia
26, Female	53	Yes	No	Inpatient	Negative	Yes	No	3 days	Suspected Pneumocystis jirovecii pneumonia
48, Male	114	Yes	No	Outpatient	Positive grade 1	No	Empirical	63 days	Suspected miliary TB
36, Male	54	Yes	No	Outpatient	Positive grade 3	Yes	Empirical	79 days	Suspected TB meningitis
38, Female	121	Yes	No	Outpatient	Negative	No	Empirical	72 days	Suspected miliary TB
60, Female	96	No	No	Outpatient	Negative	No	Empirical	169 days	HIV related cachexia (died at home)
39, Male	512	Yes	No	Outpatient	Negative	No	Directed	69 days	Confirmed TB meningitis
34, Male	495	Yes	No	Outpatient	Negative	No	No	159 days	Confirmed cryptococcal meningitis
37, Male	39	Yes	No	Outpatient	Negative	No	Empirical	83 days	Suspected cerebral toxoplasmosis
31, Male	46	Yes	No	Outpatient	Negative	Yes	Empirical	82 days	Suspected TB meningitis
35, Female	107	Yes	No	Outpatient	Negative	No	No	27 days	Suspected cerebral toxoplasmosis
36, Male	80	No	No	Outpatient	Negative	Yes	Empirical	26 days	Suspected TB meningitis

^aOn enrolment
^bCough, fever, weight loss or night sweats in last month
^cThree patients had directed therapy based on positive Xpert MTB/RIF assay on sputum
^dDays after study enrolment
^eLikely cause of death determined by attending clinician at time of death, unaware of LF-LAM result. Insufficient laboratory support to confirm diagnosis in most cases. Confirmed TB based on positive Xpert MTB/RIF assay of sputum. Confirmed cryptococcal meningitis based on India ink of cerebrospinal fluid. Suspected cerebral toxoplasmosis based on CT imaging results and clinical features. Suspected Pneumocystis jirovecii pneumonia based on clinical and radiological features
ART antiretroviral therapy, IPT isoniazid prophylaxis therapy LF-LAM lateral flow lipoarabinomannan, TB tuberculosis

ISSN: 1741-7015