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Table 2 Public health impact of vaccines related to non-health outcomes

From: The public health value of vaccines beyond efficacy: methods, measures and outcomes

Non-health related evaluations of impact of vaccines

Traditional evaluations

Additional ‘broader’ evaluations

Methods

Cost-effectiveness analysis, informed by clinical trials and costing studies

Extended cost effectiveness analysis, informed by quasi-experiments

Measures and outcomes

Healthcare cost savings

Care-related productivity gains

Health gains

Outcome- and behaviour-related productivity gains

Community health externalities (e.g. improved health outcomes in unvaccinated community members)

Improved economic outcomes at the household and societal levels

Reduction in tourism loss

Averted outbreaks

Reduced health system disruption and impact on other diseases