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Fig. 5 | BMC Medicine

Fig. 5

From: A 13-gene expression-based radioresistance score highlights the heterogeneity in the response to radiation therapy across HPV-negative HNSCC molecular subtypes

Fig. 5

Correlation of biological hallmarks with the radioresistance (RadR) score and their distribution with molecular subtypes in human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC). a The RadR score was correlated to the enrichment scores (ESs) of 48 hallmarks gene sets in 421, 179, and 82 HPV-negative HNSCC from TCGA, GSE65858, and GSE39366, respectively. The 14 hallmarks significantly (P < 0.05) correlated in all three datasets are shown. b ESs of hallmarks which were positively correlated to the RadR score were compared between the four molecular subtypes of HNSCC in the three datasets. At: atypical; Ba: basal; Cl: classical; Me: mesenchymal

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