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Table 1 Parameters used in the dynamic transmission model

From: Cost-effectiveness analysis of quadrivalent seasonal influenza vaccines in England

Parameter

Value and uncertainty

Source

Efficacy against B strain(s)

 TIIV and LAIV, < 65 years

42%

[3]

 TIIV and LAIV, 65+ years

28%

[3]

 QIIV and QLAIV, < 65 years §

70% (min. 50%, max. 90%)

[3]

 QIIV and QLAIV, 65+ years §

46% (min. 30%, max. 70%)

[3]

Influenza vaccination coverage

 Low-risk < 5 years §

33.7% (±10%)

[17]

 Low-risk 5–16 years §

54.9% (±10%)

[17]

 Clinical risk < 6 months–64 years §

45.1% (±10%)

[17]

 65+ years §

71.0% (±10%)

[17]

Health care resource costs

 GP consultation

£46, lognormal (mean 46, standard deviation 8.4)

[3]

 Inpatient admission

£1050, lognormal (mean 1050, standard deviation 192.1)

[3]

  1. The § symbol denotes that the parameter was used in the sensitivity analysis