Fig. 2

Modeling workflow and data inputs for the modeling analysis obtained from literature searches and publicly available databases. a The top schematic depicts the hierarchical modeling steps employed to quantify the expected impacts of MDA-based intervention programs to predict timelines to achieve the elimination of lymphatic filariasis (LF) from an endemic country. b The bottom diagram shows the steps, mainly involving geostatistical mapping, on how the data inputs required to initialize the LF model were obtained from several databases, either publicly available or created for this study from literature searches. Note that although we began examining the development of an ABR smooth map, the sparseness of ABR data precluded their reliable construction for use in this study. We instead used model fits to mf prevalence in a site to estimate ABR input values (see Methods)