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Table 1 Patient and tumor clinicopathological characteristics of 601 samples

From: A 25-gene classifier predicts overall survival in resectable pancreatic cancer

Characteristics

All (n = 601)

Age at diagnosis, years

  ≤ 60

118 (32%)

  > 60

246 (68%)

Sex

 Female

170 (46%)

 Male

197 (54%)

AJCC Stage

 1

62 (12%)

 2

431 (84%)

 3

10 (2%)

 4

12 (2%)

Pathological type

 Ductal

537 (98%)

 Othera

11 (2%)

Pathological grade

 1

33 (12%)

 2

154 (55%)

 3

91 (32%)

 4

2 (1%)

Pathological tumor size (pT)

 pT1

18 (5%)

 pT2

62 (16%)

 pT3

302 (77%)

 pT4

11 (3%)

Pathological lymph node status (pN)

 Negative

141 (31%)

 Positive

310 (69%)

Collisson subtypes

 Classical

234 (39%)

 Exocrine-like

211 (35%)

 Quasi-mesenchymal

156 (26%)

Moffitt subtypes, ‘type’

 Basal-like

232 (39%)

 Classical

369 (61%)

Bailey subtypes

 ADEX

140 (23%)

 Immunogenic

104 (17%)

 Pancreatic progenitor

142 (24%)

 Squamous

215 (36%)

Deceased

354 (59%)

2-year OS (95% CI)

40% (36–45)

Median OS, months (range)

20 (1–156.4)

  1. aOther: 8 neuroendocrine tumors, 2 acinar cell carcinomas, 1 intraductal tubulopapillary neoplasm
  2. ADEX aberrantly differentiated endocrine exocrine, AJCC American Joint Committee on Cancer, CI confidence interval, OS overall survival