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Fig. 1 | BMC Medicine

Fig. 1

From: Is Graves’ disease a primary immunodeficiency? New immunological perspectives on an endocrine disease

Fig. 1

Interplay of factors influencing the pathophysiology of Graves’ disease. Ab antibodies, APC antigen presenting cell, BAFF B-lymphocyte activating factor, CD cluster of differentiation, CTLA cytotoxic T-lymphocyte-associated protein, CXCL C-X-C motif chemokine, FCRL Fc receptor-like protein 3, FOXP3 forkhead box P3, HCV hepatitis C virus, HIV human immunodeficiency virus, HLA human leukocyte antigen, IL interleukin, IFN interferon, OPN osteopontin, PTPN protein tyrosine phosphatase, TG thyroglobulin, TPO thyroperoxidase, TRAb thyrotropin related antibodies, TSH-R thyroid-stimulating hormone receptor

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