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Fig. 7 | BMC Medicine

Fig. 7

From: A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria

Fig. 7

Summary of the observed ACPR28 by estimated artefenomel concentration at day 7 together with the logistic regression model predictions. The dots and error bars represent the observed ACPR28 with 90% CI for five artefenomel concentration bins (categories). The lines represent the final logistic regression model predictions taking into account the median artefenomel Cday7, as well as the median piperaquine Cday7 and median baseline parasitaemia, for each bin. Number of patients per bin: Africa ≤ 5 years n = 53, Africa > 5 years n = 15, Asia n = 20

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