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Fig. 8 | BMC Medicine

Fig. 8

From: A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria

Fig. 8

Estimated exposure–ACPR28 relationship for the combination of artefenomel with piperaquine for a baseline parasitaemia of 10,000 parasites/μL. a African patients, b Vietnamese patients, 3D representation; blue highlights the ACPR28 > 0.95. The shaded area shows the concentrations required to achieve a probability of ACPR28 > 0.95

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