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Table 1 Demographics and clinical characteristics of the study participants

From: Rapid diagnosis of new and relapse tuberculosis by quantification of a circulating antigen in HIV-infected adults in the Greater Houston metropolitan area

 

Total patients

All non-TB controls (N = 50)

All TB cases (N = 60)

TB cases

 

Culture-positive (n = 48)

Culture-negative (n = 12)

p value

Age, years (IQR)a

39 (34–46)

41 (34–46)

37 (34–48)

37 (34–48)

38 (33–48)

0.470b/0.978c

Sex, male (%)a

82 (74.5)

36 (72.0)

46 (76.7)

35 (72.9)

11 (91.7)

0.662b/0.262c

Race: no. (%)a

     

0.749b/0.713c

 Black

72 (65.5)

36 (72.0)

36 (60.0)

28 (58.3)

8 (66.7)

 

 White

16 (14.5)

5 (10.0)

11 (18.3)

10 (20.8)

1 (8.3)

 

 Hispanic

20 (18.2)

8 (16.0)

12 (20.0)

9 (18.8)

3 (25.0)

 

 Asian or Pacific Islander

2 (1.8)

1 (2.0)

1 (1.7)

1 (2.1)

– (–)

 

CD4 T cells/μL (IQR)a

110 (39–320)

127 (56–358)

99 (35–280)

73 (35–257)

237 (16–458)

0.364b/0.260c

Log10 HIV copies/mL (IQR)a

5.3 (4.6–5.6)

5.4 (4.6–5.7)

5.1 (4.3–5.6)

5.5 (5.0–5.8)

3.9 (2.8–5.5)

0.309b/0.002c

TB disease site: no. (%)a

     

0.013c

 PTB

30 (50.0)

 

30 (50.0)

20 (41.7)

10 (83.3)

 

 EPTB

37 (33.6)

 

9 (15.0)

7 (14.9)

2 (16.7)

 

 PTB and EPTB

47 (42.7)

 

21 (35.0)

21 (46.8)

– (–)

 

History of previous TB: no. (%)a

24 (21.8)

15 (30.0)

9 (15.0)

7 (14.6)

2 (16.7)

0.060b/> 0.999c

AFB smear positive: no. (%)a

13 (21.7)

 

12 (20.0)

12 (25.0)

1 (8.3)d

CXR cavitary lesions: no. (%)a

14 (23.3)

 

14 (23.3)

12 (31.6)

2 (23.3)

0.542c

  1. Data, no. (% or IQR)
  2. IQR interquartile range, AFB acid-fast bacilli, CXR chest X-ray, PTB pulmonary TB, EPTB extrapulmonary TB
  3. aPercentage or interquartile range of corresponding column population
  4. b p value of Student t test, Mann-Whitney U test, or chi-square test for difference between All non-TB controls and All TB cases
  5. c p value of chi-square test for difference between culture-positive and culture-negative TB cases
  6. dOne culture-negative TB case was marked AFB-positive with a “rare bacilli” notation