From: Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study
 | Univariablea, OR (95% CI) | Multivariable (Clinical factors only), OR (95% CI), n = 1370 | Multivariable (All factors), OR (95% CI), n = 907 |
---|---|---|---|
Maternal age (per 5 year), n = 1409 | 0.90 (0.82–1.00) | 0.79 (0.71–0.88) | 0.81 (0.71–0.93) |
Multiparous, n = 1409 | 3.22 (2.54–4.07) | 3.54 (2.75–4.55) | 4.23 (3.04–5.88) |
Previous history of GDM or PE, n = 786 | 0.58 (0.36–0.91) |  |  |
SBP (per 10 mmHg), n = 1387 | 0.77 (0.69–0.85) | 0.82 (0.73–0.91) | 0.84 (0.73–0.97) |
BMI (per 5 kg/m2), n = 1409 | 0.84 (0.74–0.94) | 0.85 (0.74–0.97) |  |
Mid-arm circumference (per 1 cm) n = 1398 | 0.96 (0.94–0.99) |  |  |
Sum of skinfolds (per 1 cm), n = 1390 | 0.94 (0.91–0.98) |  |  |
Biomarkers | |||
 HbA1c (per 1 mmol/mol), n = 949 | 0.90 (0.87–0.94) |  | 0.90 (0.86–0.94) |
 Insulin (per doubling, log2 of mU/L), n = 1017 | 0.86 (0.78–0.94) |  |  |
 Adiponectin (per doubling, log2 of μg/mL), n = 1013 | 1.34 (1.16–1.56) |  | 1.40 (1.18–1.66) |
 gGT (per doubling, log2 of U/L), n = 1015 | 0.78 (0.67–0.89) |  |  |
 SHBG (per 1 nmol/L), n = 1004 | 1.00 (1.00–1.00) |  |  |
AUROC |  | 0.69 (0.66–0.71) | 0.73 (0.69–0.76) |
Internal validation AUROC |  | 0.68 (0.65–0.71) | 0.72 (0.68–0.76) |