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Table 2 Baseline host iron status using two definitions of iron deficiency and infection markers (n = 1673, excluding 281 non-menarcheal)

From: Effects of long-term weekly iron and folic acid supplementation on lower genital tract infection – a double blind, randomised controlled trial in Burkina Faso

Infection

N

Replete (%)

Deficient (%)

Unadjusted

Adjusteda

RR (95% CI)

P valueb

Nc

RR (95% CI)

P value

Adjusted ferritin

 BVd

1347

   

0.127

1326

 

0.032

 Nugent 7–10e

1347

142/1151 (12.3)

15/175 (8.6)

1.44 (0.87–2.39)

0.168

1326

1.53 (0.92–2.54)

0.104

 Nugent 4–6e

1347

108/1151 (9.4)

11/175 (6.3)

1.49 (0.82–2.72)

0.203

1326

1.47 (0.81–2.68)

0.210

 Nugent 0–3e

1347

901/1151 (78.3)

149/175 (85.1)

0.92 (0.86–0.99)

0.036

1326

0.92 (0.86–0.98)

0.016

 Vaginal discharge

1673

21/1430 (1.5)

8/214 (3.7)

0.39 (0.18–0.88)

0.044

1644

0.41 (0.18–0.92)

0.030

 pH ≥ 4.5

1371

608/1166 (52.1)

86/183 (47.0)

1.11 (0.94–1.31)

0.204

1349

1.11 (0.94–1.30)

0.222

sTfR/log ferritin ratio > 5.6

 BVd

1347

   

0.513

1324

 

0.224

 Nugent 7–10e

1347

127/1030 (12.3)

30/294 (10.2)

1.21 (0.83–1.76)

0.358

1324

1.25 (0.86–1.83)

0.239

 Nugent 4–6e

1347

95/1030 (9.2)

24/294 (8.2)

1.13 (0.74–1.73)

0.644

1324

1.12 (0.73–1.71)

0.619

 Nugent 0–3e

1347

808/1030 (78.4)

240/294 (81.6)

0.96 (0.90–1.02)

0.255

1324

0.96 (0.90–1.02)

0.231

 Vaginal discharge

1673

18/1270 (1.4)

11/372 (3.0)

0.48 (0.23–1.01)

0.070

1642

0.49 (0.23–1.04)

0.062

 pH ≥ 4.5

1371

551/1044 (52.8)

144/303 (47.5)

1.11 (0.97–1.27)

0.117

1347

1.11 (0.97–1.26)

0.126

  1. aAdjusted for MUAC
  2. bFishers Exact Test
  3. cNumber of observations in adjusted analysis
  4. dGlobal test (Fishers/ordinal regression) for BV as 3-category outcome
  5. eEach group compared to both other groups
  6. BV bacterial vaginosis, sTfR serum transferrin receptor