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Table 2 Baseline host iron status using two definitions of iron deficiency and infection markers (n = 1673, excluding 281 non-menarcheal)

From: Effects of long-term weekly iron and folic acid supplementation on lower genital tract infection – a double blind, randomised controlled trial in Burkina Faso

Infection N Replete (%) Deficient (%) Unadjusted Adjusteda
RR (95% CI) P valueb Nc RR (95% CI) P value
Adjusted ferritin
 BVd 1347     0.127 1326   0.032
 Nugent 7–10e 1347 142/1151 (12.3) 15/175 (8.6) 1.44 (0.87–2.39) 0.168 1326 1.53 (0.92–2.54) 0.104
 Nugent 4–6e 1347 108/1151 (9.4) 11/175 (6.3) 1.49 (0.82–2.72) 0.203 1326 1.47 (0.81–2.68) 0.210
 Nugent 0–3e 1347 901/1151 (78.3) 149/175 (85.1) 0.92 (0.86–0.99) 0.036 1326 0.92 (0.86–0.98) 0.016
 Vaginal discharge 1673 21/1430 (1.5) 8/214 (3.7) 0.39 (0.18–0.88) 0.044 1644 0.41 (0.18–0.92) 0.030
 pH ≥ 4.5 1371 608/1166 (52.1) 86/183 (47.0) 1.11 (0.94–1.31) 0.204 1349 1.11 (0.94–1.30) 0.222
sTfR/log ferritin ratio > 5.6
 BVd 1347     0.513 1324   0.224
 Nugent 7–10e 1347 127/1030 (12.3) 30/294 (10.2) 1.21 (0.83–1.76) 0.358 1324 1.25 (0.86–1.83) 0.239
 Nugent 4–6e 1347 95/1030 (9.2) 24/294 (8.2) 1.13 (0.74–1.73) 0.644 1324 1.12 (0.73–1.71) 0.619
 Nugent 0–3e 1347 808/1030 (78.4) 240/294 (81.6) 0.96 (0.90–1.02) 0.255 1324 0.96 (0.90–1.02) 0.231
 Vaginal discharge 1673 18/1270 (1.4) 11/372 (3.0) 0.48 (0.23–1.01) 0.070 1642 0.49 (0.23–1.04) 0.062
 pH ≥ 4.5 1371 551/1044 (52.8) 144/303 (47.5) 1.11 (0.97–1.27) 0.117 1347 1.11 (0.97–1.26) 0.126
  1. aAdjusted for MUAC
  2. bFishers Exact Test
  3. cNumber of observations in adjusted analysis
  4. dGlobal test (Fishers/ordinal regression) for BV as 3-category outcome
  5. eEach group compared to both other groups
  6. BV bacterial vaginosis, sTfR serum transferrin receptor