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Table 3 Lower genital tract infection indicators in pregnant (ANC1) and non-pregnant (FIN) cohorts by trial arm

From: Effects of long-term weekly iron and folic acid supplementation on lower genital tract infection – a double blind, randomised controlled trial in Burkina Faso

Assessment Infection marker N Trial arm Unadjusted Adjusteda
Iron (%) Control (%) RR (95% CI) P valueb Nc RR (95% CI) P valuec
Pregnant Bacterial vaginosisd 298     0.776 245   0.704
ANC1 Nugent 7–10e 298 12/152 (7.9) 9/146 (6.2) 1.28 (0.56–2.95) 0.653 245 0.93 (0.33–2.56) 0.881
N = 315 Nugent 4–6e 298 17/152 (11.2) 19/146 (13.0) 0.86 (0.47–1.59) 0.723 245 0.94 (0.47–1.88) 0.858
  Nugent 0–3e 298 123/152 (80.9) 118/146 (80.8) 1.00 (0.90–1.12) 1 245 1.03 (0.91–1.15) 0.665
  T. vaginalis f 286 23/147 (15.6) 14/139 (10.1) 1.55 (0.83–2.90) 0.217 286 1.55 (0.83–2.90) 0.168
  Vaginal discharge 315 14/163 (8.6) 12/152 (7.9) 1.09 (0.52–2.28) 0.841 315 1.08 (0.51–2.25) 0.846
  pH ≥ 4.5 309 92/158 (58.2) 86/151 (57.0) 1.02 (0.84–1.24) 0.908 260 1.06 (0.86–1.31) 0.555
Non-pregnant Bacterial vaginosisd 671     0.588 546   0.676
FINf Nugent 7–10e 671 46/341 (13.5) 40/330 (12.1) 1.11 (0.75–1.65) 0.645 546 0.86 (0.56–1.34) 0.509
N = 877 Nugent 4–6e 671 35/341 (10.3) 26/330 (7.9) 1.30 (0.80–2.11) 0.347 546 1.21 (0.72–2.03) 0.467
  Nugent 0–3e 671 260/341 (76.2) 264/330 (80.0) 0.95 (0.88–1.03) 0.263 546 0.99 (0.90–1.08) 0.806
  T. vaginalis f 716 20/360 (5.6) 15/356 (4.2) 1.32 (0.69–2.53) 0.489 716 1.30 (0.67–2.50) 0.432
  Vaginal discharge 874 49/425 (11.5) 31/449 (6.9) 1.67 (1.09–2.57) 0.019 874 1.63 (1.06–2.51) 0.026
  1. aAdjusted for baseline infection and use of antibiotics in previous 3 months
  2. bFishers exact test
  3. cLogistic regression
  4. dEach group compared to both other groups
  5. eExcludes those less than 6 months post menarcheal
  6. fBaseline not available