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Table 5 Mean number of health centre antibiotic treatments in non-pregnant cohort by infection diagnosis and trial arm from enrolment to FIN

From: Effects of long-term weekly iron and folic acid supplementation on lower genital tract infection – a double blind, randomised controlled trial in Burkina Faso

Infection indication Iron Control Iron per 50 visits
n = 26,473
Control per 50 visits
n = 27,633
Incidence ratioa
(95% CI)
P value PFDRb
Malariac 41 28 0.077 0.051 1.53 (0.94–2.47) 0.084 0.278
Respiratory 75 87 0.142 0.157 0.90 (0.66–1.23) 0.503 0.719
Locald 75 57 0.142 0.103 1.37 (0.97–1.94) 0.071 0.278
Gastrointestinale 62 30 0.117 0.054 2.16 (1.39–3.34) <0.001 0.005
Urinary tractf 10 9 0.019 0.016 1.16 (0.47–2.86) 0.747 0.934
STIg 13 7 0.025 0.013 1.94 (0.77–4.86) 0.158 0.292
Genitalh 15 16 0.028 0.029 0.98 (0.48–1.98) 0.952 0.993
Dental 11 5 0.021 0.009 2.30 (0.80–6.62) 0.123 0.292
Meningitis 0 3 0 0.005 0 (NA) 0.993 0.993
Miscellaneousi 29 42 0.055 0.076 0.72 (0.45–1.16) 0.175 0.292
  1. aIncidence ratio was computed using Poisson regression with the number of visits as the exposure period
  2. b P value adjusted for multiple testing using false discovery rate method [26]
  3. cAntibiotics in addition to anti-malarial treatment
  4. dNon-enteric and non-respiratory, includes ear, skin, ophthalmic, abscess, wounds, local trauma, sinusitis, mastoiditis, keloid, scalp ringworm
  5. eDysentry, typhoid, enteritis, intestinal parasitosis, gastric ulcer, gastroenteritis, diarrhoea and abdominal pain, vomiting and abdominal pain, amoebiasis, colopathy, sub-occlusion
  6. fCystitis, dysuria
  7. gIncludes syphilis, trichomoniasis
  8. hUpper or lower genital infection
  9. iItching, colic, headache, generalised or localised pain, fever, vomiting only, anaemia, anxiety, neuralgia, spasms, urticarial, plus non-infectious specific diagnoses: cancers, fertility problems, angina, self-medication, allergy, burns, renal stones, contraception, thyroid and cardiac diseases, epilepsy, filariasis, foreign body, venomous bites, fractures, migraine, HIV, varicella, mumps, prophylactic and non-classifiable: includes three uncertain descriptors, or absent statement
  10. PFDR positive false discovery rate, STI sexually transmitted infection