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Table 5 Mean number of health centre antibiotic treatments in non-pregnant cohort by infection diagnosis and trial arm from enrolment to FIN

From: Effects of long-term weekly iron and folic acid supplementation on lower genital tract infection – a double blind, randomised controlled trial in Burkina Faso

Infection indication

Iron

Control

Iron per 50 visits

n = 26,473

Control per 50 visits

n = 27,633

Incidence ratioa

(95% CI)

P value

PFDRb

Malariac

41

28

0.077

0.051

1.53 (0.94–2.47)

0.084

0.278

Respiratory

75

87

0.142

0.157

0.90 (0.66–1.23)

0.503

0.719

Locald

75

57

0.142

0.103

1.37 (0.97–1.94)

0.071

0.278

Gastrointestinale

62

30

0.117

0.054

2.16 (1.39–3.34)

<0.001

0.005

Urinary tractf

10

9

0.019

0.016

1.16 (0.47–2.86)

0.747

0.934

STIg

13

7

0.025

0.013

1.94 (0.77–4.86)

0.158

0.292

Genitalh

15

16

0.028

0.029

0.98 (0.48–1.98)

0.952

0.993

Dental

11

5

0.021

0.009

2.30 (0.80–6.62)

0.123

0.292

Meningitis

0

3

0

0.005

0 (NA)

0.993

0.993

Miscellaneousi

29

42

0.055

0.076

0.72 (0.45–1.16)

0.175

0.292

  1. aIncidence ratio was computed using Poisson regression with the number of visits as the exposure period
  2. b P value adjusted for multiple testing using false discovery rate method [26]
  3. cAntibiotics in addition to anti-malarial treatment
  4. dNon-enteric and non-respiratory, includes ear, skin, ophthalmic, abscess, wounds, local trauma, sinusitis, mastoiditis, keloid, scalp ringworm
  5. eDysentry, typhoid, enteritis, intestinal parasitosis, gastric ulcer, gastroenteritis, diarrhoea and abdominal pain, vomiting and abdominal pain, amoebiasis, colopathy, sub-occlusion
  6. fCystitis, dysuria
  7. gIncludes syphilis, trichomoniasis
  8. hUpper or lower genital infection
  9. iItching, colic, headache, generalised or localised pain, fever, vomiting only, anaemia, anxiety, neuralgia, spasms, urticarial, plus non-infectious specific diagnoses: cancers, fertility problems, angina, self-medication, allergy, burns, renal stones, contraception, thyroid and cardiac diseases, epilepsy, filariasis, foreign body, venomous bites, fractures, migraine, HIV, varicella, mumps, prophylactic and non-classifiable: includes three uncertain descriptors, or absent statement
  10. PFDR positive false discovery rate, STI sexually transmitted infection