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Table 1 Distribution of plasma metabolic biomarkers and saturated fatty acid groups in the subcohort (n = 15919) and by sex, age and BMI: EPIC-InterAct study

From: Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study

  n Overall Subcohort Sex Age (years) BMI (kg/m2)
    Men (n = 6002) Women (n = 9917) <40 (n = 1524) 40–60 (n = 10919) ≥60 (n = 3476) <25 (n = 7052) 25–30 (n = 6255) ≥30 (n = 2502)
TC (mmol/L) 15304 5.93 (1.11) 5.92 (1.08) 5.94 (1.13) 5.25 (0.97) 5.92 (1.07) 6.29 (1.13) 5.8 (1.08) 6.05 (1.12) 6.04 (1.13)
HDL-C (mmol/L) 15306 1.50 (0.42) 1.30 (0.36) 1.61 (0.41) 1.48 (0.39) 1.50 (0.42) 1.50 (0.43) 1.63 (0.43) 1.41 (0.38) 1.33 (0.36)
LDL-C (mmol/L) 15125 3.83 (1.00) 3.90 (0.96) 3.79 (1.02) 3.29 (0.88) 3.82 (0.98) 4.11 (1.02) 3.66 (0.98) 3.97 (1.00) 3.96 (0.97)
TC/HDL-Ca 15304 4.00 (3.21–5.00) 4.63 (3.77–5.70) 3.67 (3.00–4.53) 3.50 (2.87–4.42) 4.00 (3.21–5.00) 4.27 (3.47–5.33) 3.53 (2.91–4.4) 4.31 (3.50–5.40) 4.57 (3.73–5.64)
TG (mmol/L)a 15303 1.1 (0.8–1.6) 1.3 (0.9–1.9) 1.0 (0.7–1.4) 0.9 (0.6–1.2) 1.1 (0.8–1.6) 1.3 (0.9–1.8) 0.9 (0.7–1.3) 1.2 (0.9–1.8) 1.4 (0.9–2)
ApoA1 (μmol/L) 15308 54.8 (10.4) 50.2 (8.9) 57.6 (10.2) 53.2 (10.5) 54.8 (10.3) 55.6 (10.4) 56.9 (10.7) 53.5 (9.9) 52.5 (9.5)
ApoB (μmol/L) 15295 1.94 (0.5) 2.03 (0.49) 1.89 (0.5) 1.66 (0.44) 1.94 (0.49) 2.10 (0.5) 1.83 (0.48) 2.02 (0.5) 2.06 (0.49)
ApoB/A1 15295 0.04 (0.01) 0.04 (0.01) 0.03 (0.01) 0.03 (0.01) 0.04 (0.01) 0.04 (0.01) 0.03 (0.01) 0.04 (0.01) 0.04 (0.01)
ALT (μkat/L)a 15274 0.32 (0.23–0.42) 0.38 (0.3–0.52) 0.28 (0.22–0.37) 0.27 (0.2–0.38) 0.32 (0.23–0.43) 0.32 (0.25–0.4) 0.27 (0.22–0.35) 0.33 (0.25–0.45) 0.38 (0.28–0.53)
AST (μkat/L)a 15068 0.45 (0.38–0.52) 0.48 (0.42–0.57) 0.43 (0.37–0.50) 0.40 (0.35–0.47) 0.45 (0.38–0.52) 0.47 (0.42–0.55) 0.43 (0.37–0.5) 0.45 (0.40–0.53) 0.47 (0.40–0.57)
GGT (μkat/L)a 15295 0.33 (0.23–0.53) 0.47 (0.33–0.73) 0.27 (0.22–0.40) 0.27 (0.20–0.37) 0.33 (0.23–0.53) 0.37 (0.27–0.55) 0.28 (0.22–0.42) 0.37 (0.25–0.6) 0.43 (0.28–0.68)
HbA1c (mmol/mol) 15711 36.2 (5.0) 36.4 (5.3) 36.1 (4.8) 33.6 (3.7) 36.0 (5.0) 38.0 (4.8) 35.5 (4.2) 36.4 (4.9) 37.9 (6.6)
CRP (nmol/L)a 15298 10.3 (5.05–22.1) 10.2 (5.24–20.9) 10.4 (4.95–22.8) 7.71 (3.43–18.4) 9.81 (4.86–20.9) 13.4 (6.67–27.2) 6.86 (3.52–14.4) 11.7 (6.29–22.9) 21.1 (10.9–39.6)
Odd-chain SFAs (mol%) 15919 0.63 (0.13) 0.58 (0.13) 0.65 (0.13) 0.63 (0.11) 0.62 (0.14) 0.63 (0.14) 0.65 (0.13) 0.61 (0.13) 0.60 (0.13)
Even-chain SFAs (mol%) 15919 44.6 (1.22) 44.8 (1.12) 44.5 (1.27) 44.2 (1.09) 44.6 (1.21) 44.8 (1.26) 44.4 (1.22) 44.7 (1.20) 44.9 (1.20)
Very-long-chain SFAs (mol%) 15919 0.70 (0.20) 0.69 (0.20) 0.71 (0.20) 0.70 (0.19) 0.70 (0.18) 0.72 (0.24) 0.71 (0.19) 0.70 (0.22) 0.69 (0.16)
  1. aThese metabolic markers were presented as median (interquartile range); all other metabolic markers or SFA groups were presented as mean (SD)
  2. TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TG triglycerides, ApoA1 apolipoprotein A-1, ApoB apolipoprotein B, ALT alanine transaminase, AST aspartate transaminase, GGT gamma glutamyl transferase, HbA1c haemoglobin A1c, CRP C-reactive protein, SFA saturated fatty acid