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Table 1 Baseline characteristics of all patients; comparison of insured and uninsured patients

From: Effectiveness of direct-acting antiviral therapy for hepatitis C in difficult-to-treat patients in a safety-net health system: a retrospective cohort study

Baseline characteristics

Patients, N

SVR, N

Uninsured, N

Insured, N

P a

(% of all patients)

(% of group)

(% of uninsured)

(% of insured)

All patients

512

459 (90)

289 (56)

223 (44)

NS

Sex, Male

288 (56)

252 (88)

158 (55)

130 (58)

NS

Race

    

**

 White

185 (36)

161 (87)

114 (39)

71 (32)

 

 Black

223 (44)

200 (90)

107 (37)

116 (52)

 

 Hispanic

81 (16)

76 (94)

50 (17)

31 (14)

 

 Other

23 (5)

22 (96)

18 (6)

5 (2)

 

Age, Median (interquartile range)

58 (54–62)

NA

57 (53–61)

59 (54–64)

**

BMI, Median (interquartile range)

28 (25–33)

NA

28 (25–33)

28 (25–34)

NS

Treatment-experienced

80 (16)

75 (94)

36 (12)

44 (20)

*

Cirrhosis

262 (51)

227 (87)

133 (46)

129 (58)

*

 Decompensated

56 (11)

46 (82)

27 (9)

29 (13)

NS

HCV genotype

    

NS

 Genotype 1a

309 (60)

273 (88)

168 (58)

141 (63)

 

 Genotype 1b

99 (19)

91 (92)

54 (19)

45 (20)

 

 Genotype 2

45 (9)

41 (91)

25 (9)

18 (8)

 

 Genotype 3

30 (6)

27 (90)

23 (8)

7 (3)

 

 Other genotypes

29 (6)

29 (100)

19 (7)

10 (4)

 

Treatment regimen

    

NS

 SOF + RBV

52 (10)

46 (88)

30 (10)

22 (10)

 

 SMV + SOF ± RBV

48 (9)

39 (81)

21 (7)

27 (12)

 

 DCV + SOF ± RBV

26 (5)

23 (88)

15 (5)

11 (5)

 

 LDV + SOF ± RBV

355 (69)

323 (91)

214 (74)

141 (63)

 

 OBV + PTV/r + DSV ± RBV

27 (5)

24 (89)

7 (2)

20 (9)

 

 EBR + GZR

4 (1)

4 (100)

2 (1)

2 (1)

 

HIV co-infected

54 (11)

47 (87)

21 (7)

33 (15)

**

Chronic HBV

15 (3)

14 (93)

7 (2)

8 (4)

NS

Liver or kidney transplant

23 (4)

20 (87)

9 (3)

14 (6)

NS

History of alcohol abuse

208 (41)

183 (88)

109 (38)

99 (44)

NS

History of drug abuse

255 (50)

226 (89)

141 (49)

114 (51)

NS

History of mental health disorder

194 (38)

172 (89)

113 (39)

81 (36)

NS

  1. a P value of uninsured versus insured by χ2 test for categorical variables and Mann–Whitney test for continuous variables; *P < 0.05; **P < 0.01
  2. BMI body mass index, HCV hepatitis C virus, Other genotypes genotypes 4 & 6 or patients infected with one or more genotypes, SOF sofosbuvir, RBV ribavirin, SMV simeprevir, DCV daclatasvir, LDV ledipasvir, OBV ombitasvir, PTV/r ritonavir-boosted paritaprevir, DSV dasabuvir, EBR elbasivr, GZR grazoprevir, HIV human immunodeficiency virus, HBV hepatitis B virus infection, SVR sustained virologic response, NA not available, NS not significant