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Fig. 5 | BMC Medicine

Fig. 5

From: A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis

Fig. 5

Association of HBV integration events and tumor recurrence. a Host genes with HBV integration events are significantly enriched for tumor suppressor genes [45] and cancer census genes [46]. In particular, only fusion transcripts identified in non-neoplastic tissues of patients with recurrence were enriched for tumor suppressor genes. “n” is the number of overlapped genes with tumor suppressor genes and p is Fisher’s exact test P value. b Association of the number of fusion transcripts and tumor recurrence in non-neoplastic and tumor tissues of low and high liver fibrosis. c Association of the number of fusion transcripts and cccDNA per hepatocyte or d HBV replicative activity within non-neoplastic liver and tumor tissues.

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