Table 2 Interventions – key parameter values
Intervention | Annual cost of intervention (£, 2015) | Incremental utility associated with intervention (QALY) | Relative risk of developing T2DM |
|---|---|---|---|
Pragmatic lifestyle programme | Yr 1: £203.44 Yr 2: £80.02 | 0.0189 [Beta distribution, SE: 0.001] | During intervention: IFG: 0.74/IGT: 0.74/HbA1c: 0.74 [Lognormal distribution, SE: 0.11] |
Intensive lifestyle programme | Yr 1: £1225 Yr 2: £689 Yr 3: £671 | 0.0189 [Beta distribution, SE: 0.001] | During intervention: IFG: 0.63/IGT: 0.55/HbA1c: 0.71 [Lognormal distribution, SE: 0.10 (IFG), 0.07 (IGT), 0.10 (HbA1c)] Up to 7 years post- intervention: IFG: 0.80/IGT: 0.80/HbA1c: 0.71 [Lognormal distribution, SE: 0.06 (IFG), 0.06 (IGT), 0.10 (HbA1c)] |
Metformin | £124.25 | 0.0031 [Beta distribution, SE: 0.002] | IFG: 0.82/IGT: 0.82/HbA1c: 0.62 [Lognormal distribution, SE: 0.05(IGT), 0.05 (IFG), 0.10 (HbA1c)] |