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Table 1 Basic characteristics of polymyalgia rheumatica (PMR) exposed/non-exposed and giant cell arteritis (GCA) exposed/non-exposed, stratified by steroid use in the 1-year period prior to outcome

From: Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study

  PMR GCA
Variables Present N = 12,136 n (%) Non-present N = 46,238 n (%) Present N = 2673 n (%) Non-present N = 10,423 n (%)
Follow up time; median (IQR) 9.27 (5.74–12.36) 9.59 (5.97–12.61) 9.13 (5.87–12.38) 9.97 (6.23–13.00)
Total fractures 1689 (13.92) 5173 (11.19) 371 (13.88) 1,142 (10.96)
Fracture site
 Wrist 464 (27.47) 1568 (30.31) 118 (31.81) 356 (31.17)
 Vertebra 276 (16.34) 482 (9.32) 72 (19.41) 123 (10.77)
 Humerus 220 (13.03) 693 (13.40) 35 (9.43) 145 (12.70)
 Hip 563 (33.33) 1844 (35.65) 115 (31.00) 419 (36.69)
 Other 166 (9.83) 586 (11.33) 31 (8.36) 99 (8.67)
Male, n (%) 3729 (30.73) 14,078 (30.45) 774 (28.96) 2981 (28.60)
Mean age (SD) 72.04 (9.70) 71.49 (9.52) 71.12 (9.91) 70.69 (9.76)
Body mass index, kg/m2
  < 18.5 161 (1.33) 676 (1.46) 42 (1.57) 140 (1.34)
 18.5–25 3723 (32.55) 14,031 (30.35) 795 (29.74) 3102 (29.76)
 25–30 3950 (32.55) 13,401 (28.98) 844 (31.58) 2941 (28.22)
  > 30 1919 (15.81) 6200 (13.41) 417 (15.60) 1412 (13.55)
 Missing 2383 (19.64) 11,930 (25.80) 575 (21.51) 2828 (27.13)
Current smoker
 Yes 1568 (12.92) 6045 (13.07) 500 (18.71) 1454 (13.95)
 No 9286 (76.52) 32,579 (70.46) 1858 (69.51) 7111 (68.22)
 Missing 1282 (10.56) 7614 (16.47) 315 (11.78) 1858 (17.83)
Alcohol (units per week)
 Never/Ex-drinker 2972 (24.49) 10,000 (21.63) 708 (26.49) 2329 (22.34)
 1–9 3285 (27.07) 12,087 (26.14) 705 (26.37) 2589 (24.84)
  ≥ 10 1453 (11.97) 5247 (11.35) 275 (10.29) 1105 (10.60)
 Missing 4426 (36.47) 18,904 (40.88) 985 (36.85) 4400 (42.21)
Consultation for falls 3771 (31.07) 11,504 (24.88) 849 (31.76) 2612 (25.06)
Charlson comorbidity index; median (IQR) 3 (1–4) 1 (0–3) 2 (1–4) 1 (0–3)
Proton pump inhibitors 7715 (63.57) 20,710 (44.79) 1749 (65.43) 4670 (44.80)
Bisphosphonate 1479 (12.19) 829 (1.79) 413 (15.45) 194 (1.86)
Methotrexate 706 (5.82) 211 (0.46) 122 (4.56) 53 (0.51)
> 1 Glucocorticoid prescription after index 10,738 (88.48) 5894 (12.75) 2232 (83.50) 1443 (13.84)
Glucocorticoids treatment length; Median months (IQR) 15.74 (6.51–34.36) 0.99 (0.23–3.07) 12.93 (4.01–32.49) 1.05 (0.23–5.13)