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Table 2 Calculated mg/kg of primaquine (PQ) base that would be received by children aged <12 years using the PQ regimen of Shekalaghe et al. [40] based on anthropometric data of the modelled database

From: Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria – a proposed model-derived age-based regimen for sub-Saharan Africa

  Modelled weights (kg)
Age band (years) Minimum 1st 5th 10th 25th Median 75th 90th 95th 99th Maximum
 1–2 5.5 6.5 7.4 7.9 8.9 10.0 11.5 12.8 13.6 15.2 18.2
 3–4 7.8 9.2 10.4 11.1 12.4 13.8 15.3 16.8 17.9 19.9 23.9
 5–7 10.0 11.5 13.0 14.0 15.2 17.0 19.2 21.0 22.8 26.0 32.1
 8–11 14.7 16.6 18.4 19.5 21.5 24.0 27.4 31.0 33.2 38.0 46.0
  PQ dose (mg base/kg)
PQ dose (mg base) Minimum 1st 5th 10th 25th Median 75th 90th 95th 99th Maximum
 7.5 0.41 0.49 0.55 0.59 0.65 0.75 0.84 0.95 1.01 1.15 1.37
 15 0.63 0.75 0.84 0.89 0.98 1.09 1.21 1.35 1.44 1.63 1.92
 15 0.47 0.58 0.66 0.71 0.78 0.88 0.99 1.07 1.15 1.30 1.50
 22.5 0.49 0.59 0.68 0.73 0.82 0.94 1.05 1.15 1.22 1.36 1.53
  1. PQ primaquine