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Table 2 Calculated mg/kg of primaquine (PQ) base that would be received by children aged <12 years using the PQ regimen of Shekalaghe et al. [40] based on anthropometric data of the modelled database

From: Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria – a proposed model-derived age-based regimen for sub-Saharan Africa

 

Modelled weights (kg)

Age band (years)

Minimum

1st

5th

10th

25th

Median

75th

90th

95th

99th

Maximum

 1–2

5.5

6.5

7.4

7.9

8.9

10.0

11.5

12.8

13.6

15.2

18.2

 3–4

7.8

9.2

10.4

11.1

12.4

13.8

15.3

16.8

17.9

19.9

23.9

 5–7

10.0

11.5

13.0

14.0

15.2

17.0

19.2

21.0

22.8

26.0

32.1

 8–11

14.7

16.6

18.4

19.5

21.5

24.0

27.4

31.0

33.2

38.0

46.0

 

PQ dose (mg base/kg)

PQ dose (mg base)

Minimum

1st

5th

10th

25th

Median

75th

90th

95th

99th

Maximum

 7.5

0.41

0.49

0.55

0.59

0.65

0.75

0.84

0.95

1.01

1.15

1.37

 15

0.63

0.75

0.84

0.89

0.98

1.09

1.21

1.35

1.44

1.63

1.92

 15

0.47

0.58

0.66

0.71

0.78

0.88

0.99

1.07

1.15

1.30

1.50

 22.5

0.49

0.59

0.68

0.73

0.82

0.94

1.05

1.15

1.22

1.36

1.53

  1. PQ primaquine