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Table 1 Clinical and demographic characteristics of the study population

From: Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin

 

Uncomplicated term delivery

Before PPROM

P value (UTC vs. before PPROM)

After PPROM

P value (before PPROM vs. after PPROM)

P value all

Total number

20

15

 

87

  

Age (years)

33 (31–34)

34 (30–37)

0.6410

33 (32–34)

0.79

0.9279

Ethnicity n (%)

 Caucasian

10 (50%)

6 (40%)

 

38 (44%)

  

 Black

5 (25%)

3 (20%)

0.6393

20 (23%)

0.8796

0.9207

 Asian

5 (25%)

6 (40%)

 

29 (33%)

  

GA first sample (weeks)

28+2 (28+1–29+0)

32+0 (27+0–34+0)

0.1871

28+1 (25+1–33+0)

0.2743

0.4504

GA at MR (weeks)

n/a

34+4 (31+0–35+2)

 

27+0 (24+6–32+4)

0.0011

 

GA at delivery (weeks)

40+1 (39+2–41+1)

34+4 (31+0–35+2)

6.12 × 10-7

30+4 (26+5–34+2)

0.0142

<0.0001

Apgar score

 1 min

9 (8–9)*

9 (8–9)*

0.6432

6 (5–9)**

0.0013

<0.0001

 5 min

10 (10–10)*

9 (9–10)*

0.0656

8 (7–9)**

0.0183

<0.0001

BW (g)

3400 (3215–3980)*

2285 (1720–2560)

0.000005

1550 (877.5–2216)

0.0140

<0.0001

Admission to neonatal unit

0 (0%)

3 (20%)

0.069519

59 (68%)

0.00094

<0.0001

Latency

 PPROM to delivery (days)

n/a

1 (0–4)

 

4 (2–9)

0.0212

 
  1. Data presented as median (interquartile range) or number (%)
  2. BMI body mass index, BW birth weight, GA gestational age, MR membrane rupture, n/a not applicable, PPROM Preterm prelabour rupture of the fetal membranes
  3. P values: t-test/Mann–Whitney U (depending upon distribution), Fisher’s exact for proportional data, ANOVA for multiple comparisons
  4. Missing data * n = 5, **n = 15