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Table 2 Multivariate analysis (logistic regression model) of clinical and laboratory factors at admission associated with mortality at 72 h of randomisation

From: Lactate clearance as a prognostic marker of mortality in severely ill febrile children in East Africa

  Categories Adjusted OR of death (95% CI) p valuea
Age (months) ≥ 12 1.00 (Ref.)b < 0.01
< 12 1.98 (1.22, 3.2)
Gender Male 1.00 (Ref.)b 0.96
Female 1.01 (0.71, 1.46)
Site Mbale 1.00 (Ref.)b  
Kilifi 1.56(0.76, 3.23) 0.23
Mulago 1.47 (0.80, 2.70) 0.21
Soroti 1.16 (0.64, 2.14) 0.63
Lacor
Teule 2.04 (0.87, 4.76) 0.10
Lactate stratum (mmol/L) No (< 2.5) 1.00 (Ref.)b  
Moderate (2.5–5) 1.28 (0.62, 2.63) 0.50
Severe (≥ 5) 6.96 (3.52, 13.76) < 0.001
Level of consciousness Alert 1.00 (Ref.)b  
Prostration 1.41 (0.72, 2.76) 0.31
Coma 6.87 (3.36, 14.04) < 0.001
BUN (mmol/L)d < 7.14 1.00 (Ref.)b < 0.001
≥ 7.14 2.92 (1.84, 4.62)
Malaria No 1.00 (Ref.)b < 0.001
Yes 0.45 (0.29, 0.69)
Severe anaemia (Hb < 5 g/dL) No 1.00 (Ref.)b 0.37
Yes 0.81 (0.50, 1.29)
Hyperglycaemiac (glucose ≥ 8.3 mmol/L) No 1.00 (Ref.)2 0.55
Yes 0.84 (0.55, 1.30)
HIV No 1.00 (Ref.)2 0.05
Yes 2.16 (1.01, 4.60)
  1. aWald test p values
  2. bRef: Reference group
  3. cModerate evidence of interaction, stratum-specific odds ratios are shown in Additional file 1
  4. dBlood Urea Nitrogen